Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SENP2_HUMAN
Description:SUMO1/sentrin/SMT3 specific peptidase 2 [Source:HGNC Symbol;Acc:23116]
Location:chr3 q27.2
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y216EEREKyRKLLEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S496LKYLDsMGQKGPeptidase_C48PhosphoSitePlus
S34RRRSDsTLFSTPhosphoSitePlus
S168GGRRHsKGNPEPhosphoSitePlus
Y130NGISDyPKIRVPhosphoSitePlus
S284RGPLCsLRSEKPhosphoSitePlus
T35RRSDStLFSTVPhosphoSitePlus
S344LRRKVsIIETKPhosphoSitePlus
S231SGHGNsVCPVTPhosphoSitePlus
Y239PVTSNyHSSQRPhosphoSitePlus
Y558CKYADyISRDKPeptidase_C48PhosphoSitePlus
S292SEKRCsKGKITPhosphoSitePlus
Y493KKCLKyLDSMGPeptidase_C48PhosphoSitePlus
S333RLRLGsGSNGLPhosphoSitePlus; HPRD
S287LCSLRsEKRCSPhosphoSitePlus

Dephosphorylation site
SENP2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000296257P540LCOSMICLung Cancer20668451
ENSP00000296257W113CCOSMICLung Cancer20668451
ENSP00000296257E214DCOSMICHead and Neck Cancer21798893

Differential expressed protein
SENP2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SENP2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SENP2_HUMANDVL1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03013RNA transport
hsa04310Wnt signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0016604nuclear bodyIEAcellular_component
GO:0005643nuclear poreIDAcellular_component
GO:0016605PML bodyIEAcellular_component
GO:0015031protein transportIEAbiological_process
GO:0019904protein domain specific bindingIEAmolecular_function
GO:0007507heart developmentIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0009950dorsal/ventral axis specificationIEAbiological_process
GO:0051028mRNA transportIEAbiological_process
GO:0008234cysteine-type peptidase activityIEAmolecular_function
GO:0051246regulation of protein metabolic processIEAbiological_process
GO:0032091negative regulation of protein bindingIEAbiological_process
GO:0016929SUMO-specific protease activityIDAmolecular_function
GO:0001934positive regulation of protein phosphorylationIEAbiological_process
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0035562negative regulation of chromatin bindingIEAbiological_process
GO:0006508proteolysisIEAbiological_process
GO:0016926protein desumoylationIEAbiological_process
GO:0031965nuclear membraneIEAcellular_component
GO:0030111regulation of Wnt receptor signaling pathwayNASbiological_process
GO:0005737cytoplasmIEAcellular_component


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