| UniProt/SwissProt ID: | SELPL_HUMAN |
| Description: | selectin P ligand [Source:HGNC Symbol;Acc:10722] |
| Location: | chr12 q24.11 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T73 | DTTPLtGPGTP | PhosphoSitePlus | |
| T406 | EGDDLtLHSFL | PhosphoSitePlus | |
| T159 | TRLTAtEAQTT | PhosphoSitePlus | |
| T393 | KSPGLtPEPRE | PhosphoSitePlus; phosphoELM | |
| T67 | MLRNStDTTPL | PhosphoSitePlus | |
| T82 | TPESTtVEPAA | PhosphoSitePlus | |
| T383 | KSPGLtPEPRE | HPRD | |
| T157 | QTTRLtATEAQ | PhosphoSitePlus | |
| S379 | LSKAKsPGLTP | HPRD | |
| S409 | DLTLHsFLP__ | PhosphoSitePlus | |
| S389 | LSKAKsPGLTP | PhosphoSitePlus; phosphoELM | |
| T81 | GTPEStTVEPA | PhosphoSitePlus | |
| T69 | RNSTDtTPLTG | PhosphoSitePlus | |
| Dephosphorylation site |
| SELPL_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000373614 | R64K | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| SELPL_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SELPL_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| SELPL_HUMAN | SEPP1_HUMAN | ligand -> receptor | HPMR |
| SELPL_HUMAN | LYAM2_HUMAN | ligand -> receptor | HPMR |
| SELPL_HUMAN | LYAM2_HUMAN | other | KEGG |
| SELPL_HUMAN | SEPP1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04514 | Cell adhesion molecules (CAMs) |
| hsa05150 | Staphylococcus aureus infection |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005102 | receptor binding | NAS | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0007155 | cell adhesion | TAS | biological_process |
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0071354 | cellular response to interleukin-6 | IDA | biological_process |
| GO:0050902 | leukocyte adhesive activation | IEA | biological_process |
| GO:0051635 | bacterial cell surface binding | TAS | molecular_function |
| GO:0016020 | membrane | TAS | cellular_component |
| GO:0016021 | integral to membrane | TAS | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0050901 | leukocyte tethering or rolling | IEA | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0050902 | leukocyte adhesive activation | ISS | biological_process |
| GO:0050900 | leukocyte migration | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |