Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SCRB1_HUMAN
Description:scavenger receptor class B, member 1 [Source:HGNC Symbol;Acc:1664]
Location:chr12 q24.31
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S493QAYSEsLMTSAHPRD
T175AFMNRtVGEIMPhosphoSitePlus
Y490EAIQAySESLMHPRD
T496SESLMtSAPKGHPRD
S491AIQAYsESLMTHPRD

Dephosphorylation site
SCRB1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000261693N317SCOSMICRenal Cancer

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000261693Hepatocellular CarcinomaMetastasiscell lineUp2.119016532

Hyperphosphorylation site
SCRB1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTSS1_HUMANSCRB1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05160Hepatitis C
hsa04977Vitamin digestion and absorption
hsa04976Bile secretion
hsa04975Fat digestion and absorption
hsa04145Phagosome

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0070506high-density lipoprotein particle receptor activitIDAmolecular_function
GO:0006629lipid metabolic processTASbiological_process
GO:0006869lipid transportIEAbiological_process
GO:0042632cholesterol homeostasisISSbiological_process
GO:0070508cholesterol importISSbiological_process
GO:0070328triglyceride homeostasisISSbiological_process
GO:0001935endothelial cell proliferationIEAbiological_process
GO:0006707cholesterol catabolic processIEAbiological_process
GO:0034186apolipoprotein A-I bindingIPImolecular_function
GO:0001530lipopolysaccharide bindingIDAmolecular_function
GO:0005901caveolaTAScellular_component
GO:0033344cholesterol effluxIEAbiological_process
GO:0051856adhesion to symbiontIMPbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0001875lipopolysaccharide receptor activityIDAmolecular_function
GO:0010867positive regulation of triglyceride biosynthetic pISSbiological_process
GO:0030301cholesterol transportIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0015914phospholipid transportIEAbiological_process
GO:0042060wound healingTASbiological_process
GO:0034185apolipoprotein bindingIPImolecular_function
GO:0015920lipopolysaccharide transportIDAbiological_process
GO:0030169low-density lipoprotein particle bindingIDAmolecular_function
GO:0010899regulation of phosphatidylcholine catabolic procesIEAbiological_process
GO:0031528microvillus membraneIEAcellular_component
GO:0010899regulation of phosphatidylcholine catabolic procesISSbiological_process
GO:0043654recognition of apoptotic cellIDAbiological_process
GO:0031663lipopolysaccharide-mediated signaling pathwayIDAbiological_process
GO:0050764regulation of phagocytosisICbiological_process
GO:0034375high-density lipoprotein particle remodelingIEAbiological_process
GO:0042632cholesterol homeostasisIEAbiological_process
GO:0051000positive regulation of nitric-oxide synthase activIDAbiological_process
GO:0033344cholesterol effluxISSbiological_process
GO:0006910phagocytosis, recognitionIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0007155cell adhesionIEAbiological_process
GO:0005887integral to plasma membraneIEAcellular_component
GO:0043691reverse cholesterol transportIEPbiological_process
GO:0034185apolipoprotein bindingIEAmolecular_function
GO:00055451-phosphatidylinositol bindingTASmolecular_function
GO:0043534blood vessel endothelial cell migrationIEAbiological_process
GO:0034383low-density lipoprotein particle clearanceIEAbiological_process
GO:0010867positive regulation of triglyceride biosynthetic pIEAbiological_process
GO:0006702androgen biosynthetic processIEAbiological_process
GO:0005901caveolaIEAcellular_component
GO:0032497detection of lipopolysaccharideIDAbiological_process
GO:0034384high-density lipoprotein particle clearanceIDAbiological_process
GO:0034375high-density lipoprotein particle remodelingISSbiological_process
GO:0015914phospholipid transportISSbiological_process
GO:0034383low-density lipoprotein particle clearanceISSbiological_process
GO:0009986cell surfaceIEAcellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0019048virus-host interactionIEAbiological_process
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0010595positive regulation of endothelial cell migrationTASbiological_process
GO:0005215transporter activityTASmolecular_function
GO:0070328triglyceride homeostasisIEAbiological_process
GO:0043691reverse cholesterol transportIEAbiological_process
GO:0008035high-density lipoprotein particle bindingIEAmolecular_function
GO:0042157lipoprotein metabolic processTASbiological_process
GO:0070508cholesterol importIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0001786phosphatidylserine bindingISSmolecular_function
GO:0010886positive regulation of cholesterol storageIDAbiological_process