Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SCAM3_HUMAN
Description:secretory carrier membrane protein 3 [Source:HGNC Symbol;Acc:10565]
Location:chr1 q22
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y83TEPKNyGSYSTPhosphoSitePlus; HPRD; RegPhos
S85PKNYGsYSTQAPhosphoSitePlus; HPRD
S32IQHRPsRQYATPhosphoSitePlus; HPRD; SysPTM
Y41ATLDVyNPFETPhosphoSitePlus
S87NYGSYsTQASAPhosphoSitePlus
Y41ATRDVyNPFETEGFRRegPhos
S76PSRKLsPTEPKPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
T78RKLSPtEPKNYPhosphoSitePlus; HPRD
T37SRQYAtLDVYNPhosphoSitePlus
Y86KNYGSySTQASPhosphoSitePlus; HPRD; RegPhos
T52RKLSPtEPKNYHPRD
S91YSTQAsAAAATPhosphoSitePlus
S50PSRKLsPTEPKHPRD
Y41ATRDVyNPFETphosphoELM; RegPhos
T88YGSYStQASAAPhosphoSitePlus; HPRD
Y60KNYGSySTQASHPRD
S59PKNYGsYSTQAHPRD
T62YGSYStQASAAHPRD
Y57TEPKNyGSYSTHPRD
Y35RPSRQyATRDVphosphoELM; RegPhos
Y41ATLDVyNPFETEGFRHPRD
Y35RPSRQyATLDVPhosphoSitePlus; HPRD
Y53EPPPAyEPPAPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T46YNPFEtREPPPPhosphoSitePlus

Dephosphorylation site
SCAM3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000307275A184TCOSMICOvarian Cancer21720365
ENSP00000307275R5TCOSMICOvarian Cancer21720365
ENSP00000307275R329*COSMICOvarian Cancer21720365
ENSP00000307275A25PCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000307275Hepatocellular CarcinomaNormal vs. Cancercell lineDown0.2418646787
ENSP00000307275Hepatocellular CarcinomaNormal vs. Cancercell lineDown0.2918646787
ENSP00000307275Breast CancerNormal vs. CancertissueUp0.5420739354

Hyperphosphorylation site
SCAM3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANSCAM3_HUMANkinase -> substrateRegPhos
EGFR_HUMANSCAM3_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
SCAM3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006892post-Golgi vesicle-mediated transportTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0015031protein transportIEAbiological_process
GO:0032526response to retinoic acidIEAbiological_process
GO:0042221response to chemical stimulusIEAbiological_process
GO:0000139Golgi membraneIEAcellular_component


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