| UniProt/SwissProt ID: | SAT1_HUMAN |
| Description: | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:10540] |
| Location: | chrX p22.11 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S149 | GASDLsSEEGW | CK2a1 | RegPhos |
| S149 | GASDLsSEEGW | CK2a1-rs | RegPhos |
| T10 | VIRPAtAADCS | CK2a2 | RegPhos |
| T10 | VIRPAtAADCS | CK2a1 | RegPhos |
| S149 | GASDLsSEEGW | CK2a2 | RegPhos |
| S149 | GASDLsSEEGW | PhosphoSitePlus | |
| T10 | VIRPAtAADCS | CSNK2A2 | HPRD |
| Y90 | IGKLLyLEDFF | Acetyltransf_1 | PhosphoSitePlus |
| S149 | GASDLsSEEGW | CSNK2A1 | HPRD |
| S149 | GASDLsSEEGW | CSNK2A2 | HPRD |
| S146 | KRRGAsDLSSE | CK2_group | phosphoELM; RegPhos |
| S146 | KRRGAsDLSSE | Acetyltransf_1 | PhosphoSitePlus |
| T10 | VIRPAtAADCS | CK2a1-rs | RegPhos |
| S146 | KRRGAsDLSSE | CSNK2A2 | HPRD |
| S146 | KRRGAsDLSSE | CSNK2A1 | HPRD |
| S146 | KRRGAsDLSSE | CK2a1-rs | RegPhos |
| Y78 | GFAMYyFTYDP | Acetyltransf_1 | PhosphoSitePlus |
| Y77 | VGFAMyYFTYD | Acetyltransf_1 | PhosphoSitePlus |
| S146 | KRRGAsDLSSE | CK2a2 | RegPhos |
| S146 | KRRGAsDLSSE | CK2a1 | RegPhos |
| Y27 | KELAKyEYMEE | PhosphoSitePlus | |
| T10 | VIRPAtAADCS | CSNK2A1 | HPRD |
| S149 | GASDLsSEEGW | CK2_group | phosphoELM; RegPhos |
| T10 | VIRPAtAADCS | CK2_group | phosphoELM; RegPhos |
| Dephosphorylation site |
| SAT1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| SAT1_HUMAN do not have mutation site. |
| Differential expressed protein |
| SAT1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SAT1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CSK22_HUMAN | SAT1_HUMAN | kinase -> substrate | HPRD |
| CSK21_HUMAN | SAT1_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa01100 | Metabolic pathways |
| hsa00330 | Arginine and proline metabolism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0019809 | spermidine binding | IEA | molecular_function |
| GO:0006595 | polyamine metabolic process | TAS | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0001525 | angiogenesis | IEP | biological_process |
| GO:0034641 | cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0006595 | polyamine metabolic process | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0042127 | regulation of cell proliferation | IEA | biological_process |
| GO:0009447 | putrescine catabolic process | IEA | biological_process |
| GO:0006596 | polyamine biosynthetic process | TAS | biological_process |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0004145 | diamine N-acetyltransferase activity | IEA | molecular_function |
| GO:0005622 | intracellular | IDA | cellular_component |
| GO:0008080 | N-acetyltransferase activity | IEA | molecular_function |