Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RRAS_HUMAN
Description:related RAS viral (r-ras) oncogene homolog [Source:HGNC Symbol;Acc:10447]
Location:chr19 q13.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y66TIEDSyTKICSSRCphosphoELM
T9GAASGtGRGRPPhosphoSitePlus
Y66TIEDSyTKICSSrcRegPhos
Y66TIEDSyTKICSRasPhosphoSitePlus
Y66TIEDSyTKICSEPHB2HPRD
S201QELPPsPPSAPPhosphoSitePlus; HPRD
Y66TIEDSyTKICSEphB2phosphoELM; RegPhos
Y58YFVSDyDPTIERasPhosphoSitePlus

Dephosphorylation site
RRAS_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000246792V216ICOSMICOvarian Cancer20826764
ENSP00000246792Y66*COSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000246792Hepatocellular CarcinomaNormal vs. Cancercell lineDown0.4918646787
ENSP00000246792Hepatocellular CarcinomaNormal vs. Cancercell lineUp5.518646787
ENSP00000246792Prostate CancerMetastasistissueDown0.3118553995
ENSP00000246792Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
RRAS_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EPHB2_HUMANRRAS_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05166HTLV-I infection
hsa04530Tight junction
hsa04010MAPK signaling pathway
hsa04810Regulation of actin cytoskeleton

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006184GTP catabolic processIEAbiological_process
GO:0007264small GTPase mediated signal transductionIEAbiological_process
GO:0007265Ras protein signal transductionTASbiological_process
GO:0030336negative regulation of cell migrationIEAbiological_process
GO:0005622intracellularIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0006913nucleocytoplasmic transportIEAbiological_process
GO:0019003GDP bindingIDAmolecular_function
GO:0007268synaptic transmissionTASbiological_process
GO:0016020membraneIEAcellular_component
GO:0007165signal transductionIEAbiological_process
GO:0005525GTP bindingIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0007411axon guidanceTASbiological_process
GO:0045766positive regulation of angiogenesisIMPbiological_process
GO:0006886intracellular protein transportIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0003924GTPase activityIDAmolecular_function
GO:0015031protein transportIEAbiological_process


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