Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RPGP2_HUMAN
Description:RAP1 GTPase activating protein 2 [Source:HGNC Symbol;Acc:29176]
Location:chr17 p13.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S7FGRKRsVSFGGPhosphoSitePlus
S9RKRSVsFGGFGPhosphoSitePlus; HPRD
S665GGSQPsTTSPFPhosphoSitePlus
T510SHSMEtMVGGQPhosphoSitePlus
S589CDSTSsTPKTPPhosphoSitePlus
T572FPRLHtGSEGQPhosphoSitePlus
S45PDRPLsPPLTAPhosphoSitePlus; HPRD
S505AIRVRsHSMETPhosphoSitePlus
T593SSTPKtPDGGHPhosphoSitePlus
S588RCDSTsSTPKTPhosphoSitePlus
S507RVRSHsMETMVPhosphoSitePlus
S613SSNPSsPEICPPhosphoSitePlus; HPRD; RegPhos
S609KSETSsNPSSPPhosphoSitePlus; HPRD
S558KNQSRsPIKRRPhosphoSitePlus
S57PTMKSsEFFEMPhosphoSitePlus
T49LSPPLtAPPTMPhosphoSitePlus; HPRD
S586RARCDsTSSTPPhosphoSitePlus
S662GDSGGsQPSTTPhosphoSitePlus
T590DSTSStPKTPDPhosphoSitePlus
S564PIKRRsGLFPRPhosphoSitePlus
S612TSSNPsSPEICPhosphoSitePlus; HPRD
T587ARCDStSSTPKPhosphoSitePlus
S7FGRKRsVSFGGPKG1RegPhos
S496GGFLEsFKRAIPhosphoSitePlus
S574RLHTGsEGQGDPhosphoSitePlus
T667SQPSTtSPFKQPhosphoSitePlus
S600DGGHSsQEIKSPhosphoSitePlus
S544TKTTFsPPVVAPhosphoSitePlus; HPRD; RegPhos
S605SQEIKsETSSNPhosphoSitePlus
S56PPTMKsSEFFEPhosphoSitePlus
S668QPSTTsPFKQEPhosphoSitePlus
Y88DDYIPyPSIDEPhosphoSitePlus
T53LTAPPtMKSSEPhosphoSitePlus
Y85KNKDDyIPYPSPhosphoSitePlus

Dephosphorylation site
RPGP2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000254695P614LCOSMICOvarian Cancer21720365
ENSP00000254695D595GCOSMICHead and Neck Cancer21798893
ENSP00000389824P695ABIOMARTBreast Cancer21930507, 21930502
ENSP00000389824M360RBIOMARTBreast Cancer21930507, 21930502
ENSP00000254695M375RBIOMARTBreast Cancer21930507, 21930502
ENSP00000254695P710ABIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
RPGP2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RPGP2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANRPGP2_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
RPGP2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005829cytosolTAScellular_component
GO:0005813centrosomeIDAcellular_component
GO:0005096GTPase activator activityIEAmolecular_function
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0051056regulation of small GTPase mediated signal transduIEAbiological_process


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