| UniProt/SwissProt ID: | RIN1_HUMAN |
| Description: | Ras and Rab interactor 1 [Source:HGNC Symbol;Acc:18749] |
| Location: | chr11 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S330 | EGVPGsRGSPA | PhosphoSitePlus | |
| S333 | PGSRGsPATSP | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| Y698 | LPTTGyLVYRR | RA | PhosphoSitePlus |
| S349 | RPLLRsMSAAF | PhosphoSitePlus | |
| S609 | QELRRsLSLWE | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S258 | TSSPLsPPAVP | PhosphoSitePlus; HPRD; phosphoELM | |
| S292 | LRRESsVGYRV | PhosphoSitePlus | |
| S16 | SPGAPsPSSFT | PhosphoSitePlus; HPRD | |
| S351 | LLRSMsAAFCS | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S351 | LLRSMsAAFCS | PKD_group | RegPhos; SysPTM |
| S351 | LLRSMsAAFCS | PKD1 | phosphoELM; RegPhos; SysPTM |
| Y295 | ESSVGyRVPAG | PhosphoSitePlus | |
| S244 | EKFKRsFKVRV | PhosphoSitePlus | |
| S356 | SAAFCsLLAPE | HPRD | |
| S407 | IRQALsRARAM | PhosphoSitePlus | |
| S601 | HTLPLsPVQEL | RegPhos | |
| T253 | RVSTEtSSPLS | HPRD; phosphoELM | |
| T90 | TEPPGtFLVRK | SH2 | PhosphoSitePlus |
| T388 | VQDLLtQVRAG | PhosphoSitePlus | |
| Y701 | TGYLVyRRAEW | RA | PhosphoSitePlus |
| Y681 | YKEQGyHRLPP | RA | PhosphoSitePlus |
| S11 | ESGAGsPGAPS | PhosphoSitePlus; HPRD | |
| Y632 | LLRVAyQDPSS | RA | PhosphoSitePlus |
| T696 | HRLPTtGYLVY | RA | PhosphoSitePlus |
| T377 | MQDRHtAAGQL | PhosphoSitePlus | |
| S3 | GESG | HPRD | |
| T336 | RGSPAtSPHLG | PhosphoSitePlus | |
| Y36 | AQDPLyDVPNA | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| Y676 | FGLFLyKEQGY | RA | PhosphoSitePlus |
| T251 | KVRVStETSSP | HPRD; phosphoELM | |
| Y35 | PAQDPlYDVPN | HPRD | |
| S42 | DVPNAsGGQAG | PhosphoSitePlus | |
| S3 | ___MEsPGESG | PhosphoSitePlus | |
| S337 | GSPATsPHLGR | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| S210 | QLKARsPQELD | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S291 | LLRREsSVGYR | PhosphoSitePlus | |
| Dephosphorylation site |
| RIN1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000310406 | P686S | Ding2008 | Lung Cancer | 18948947 | ENSP00000310406 | P686S | COSMIC | Lung Cancer | 18948947 | ENSP00000310406 | Q404* | COSMIC | Lung Cancer | 20668451 | ENSP00000310406 | M372I | COSMIC | Breast Cancer | 20668451 |
| Differential expressed protein |
| RIN1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RIN1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | RIN1_HUMAN | kinase -> substrate | RegPhos |
| KPCD1_HUMAN | RIN1_HUMAN | kinase -> substrate | RegPhos |
| PKD1_HUMAN | RIN1_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| RIN1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0006897 | endocytosis | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005856 | cytoskeleton | IEA | cellular_component |