Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RIN1_HUMAN
Description:Ras and Rab interactor 1 [Source:HGNC Symbol;Acc:18749]
Location:chr11 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S330EGVPGsRGSPAPhosphoSitePlus
S333PGSRGsPATSPPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
Y698LPTTGyLVYRRRAPhosphoSitePlus
S349RPLLRsMSAAFPhosphoSitePlus
S609QELRRsLSLWEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S258TSSPLsPPAVPPhosphoSitePlus; HPRD; phosphoELM
S292LRRESsVGYRVPhosphoSitePlus
S16SPGAPsPSSFTPhosphoSitePlus; HPRD
S351LLRSMsAAFCSPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S351LLRSMsAAFCSPKD_groupRegPhos; SysPTM
S351LLRSMsAAFCSPKD1phosphoELM; RegPhos; SysPTM
Y295ESSVGyRVPAGPhosphoSitePlus
S244EKFKRsFKVRVPhosphoSitePlus
S356SAAFCsLLAPEHPRD
S407IRQALsRARAMPhosphoSitePlus
S601HTLPLsPVQELRegPhos
T253RVSTEtSSPLSHPRD; phosphoELM
T90TEPPGtFLVRKSH2PhosphoSitePlus
T388VQDLLtQVRAGPhosphoSitePlus
Y701TGYLVyRRAEWRAPhosphoSitePlus
Y681YKEQGyHRLPPRAPhosphoSitePlus
S11ESGAGsPGAPSPhosphoSitePlus; HPRD
Y632LLRVAyQDPSSRAPhosphoSitePlus
T696HRLPTtGYLVYRAPhosphoSitePlus
T377MQDRHtAAGQLPhosphoSitePlus
S3GESGHPRD
T336RGSPAtSPHLGPhosphoSitePlus
Y36AQDPLyDVPNAPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
Y676FGLFLyKEQGYRAPhosphoSitePlus
T251KVRVStETSSPHPRD; phosphoELM
Y35PAQDPlYDVPNHPRD
S42DVPNAsGGQAGPhosphoSitePlus
S3___MEsPGESGPhosphoSitePlus
S337GSPATsPHLGRPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S210QLKARsPQELDPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S291LLRREsSVGYRPhosphoSitePlus

Dephosphorylation site
RIN1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000310406P686SDing2008Lung Cancer18948947
ENSP00000310406P686SCOSMICLung Cancer18948947
ENSP00000310406Q404*COSMICLung Cancer20668451
ENSP00000310406M372ICOSMICBreast Cancer20668451

Differential expressed protein
RIN1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RIN1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANRIN1_HUMANkinase -> substrateRegPhos
KPCD1_HUMANRIN1_HUMANkinase -> substrateRegPhos
PKD1_HUMANRIN1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
RIN1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneTAScellular_component
GO:0007165signal transductionIEAbiological_process
GO:0006897endocytosisIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005856cytoskeletonIEAcellular_component


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