| UniProt/SwissProt ID: | RHG24_HUMAN |
| Description: | Rho GTPase activating protein 24 [Source:HGNC Symbol;Acc:25361] |
| Location: | chr4 q21.23 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y508 | WLPNGyVTLRD | PhosphoSitePlus | |
| T452 | EKTQTtPNGSL | ROCK1 | HPRD; RegPhos |
| S574 | NSCRSsTTTCP | ROCK1 | HPRD; RegPhos |
| T576 | CRSSTtTCPEQ | ROCK1 | HPRD; RegPhos |
| S391 | SMNNGsPTALS | ROCK1 | HPRD; RegPhos |
| S369 | NNTKDsPSRQC | PhosphoSitePlus | |
| S573 | SNSCRsSTTTC | ROCK1 | HPRD; RegPhos |
| S415 | LDVSRsPPLMV | PhosphoSitePlus; RegPhos | |
| T354 | IQKKAtMGQLQ | PhosphoSitePlus | |
| S413 | HKLDVsRSPPL | PhosphoSitePlus; RegPhos | |
| S402 | GSKTNsPKNSV | PhosphoSitePlus; RegPhos | |
| S371 | TKDSPsRQCSW | PhosphoSitePlus | |
| S437 | IVTNGsFSSSN | PhosphoSitePlus; RegPhos | |
| S627 | RATSSsDNSET | PhosphoSitePlus | |
| T624 | RSSRAtSSSDN | PhosphoSitePlus | |
| S415 | LDVSRsPPLMV | ROCK1 | HPRD; RegPhos |
| S437 | IVTNGsFSSSN | ROCK1 | HPRD; RegPhos |
| S402 | GSKTNsPKNSV | ROCK1 | HPRD; RegPhos |
| T577 | RSSTTtCPEQD | ROCK1 | HPRD; RegPhos |
| T452 | EKTQTtPNGSL | PhosphoSitePlus; RegPhos | |
| S413 | HKLDVsRSPPL | ROCK1 | HPRD; RegPhos |
| T575 | SCRSStTTCPE | ROCK1 | HPRD; RegPhos |
| S391 | SMNNGsPTALS | PhosphoSitePlus; RegPhos | |
| Dephosphorylation site |
| RHG24_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000264343 | P237S | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| RHG24_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RHG24_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | RHG24_HUMAN | kinase -> substrate | RegPhos |
| ROCK1_HUMAN | RHG24_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| RHG24_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0001525 | angiogenesis | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0005543 | phospholipid binding | IEA | molecular_function |
| GO:0005925 | focal adhesion | IEA | cellular_component |
| GO:0042995 | cell projection | IEA | cellular_component |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0051056 | regulation of small GTPase mediated signal transdu | TAS | biological_process |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005856 | cytoskeleton | IEA | cellular_component |
| GO:0030154 | cell differentiation | IEA | biological_process |
| GO:0007264 | small GTPase mediated signal transduction | TAS | biological_process |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |