Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RGS7_HUMAN
Description:regulator of G-protein signaling 7 [Source:HGNC Symbol;Acc:10003]
Location:chr1 q43
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S434LMKSDsYPRFIPKC_alphaphosphoELM
S434LMKSDsYPRFIPKCaRegPhos
S434LMKSDsYPRFIRegPhos
S434LMKSDsYPRFIPRKCAHPRD
T243RSHSPtHTPTPFlxAPhosphoSitePlus
S457KKSGNsMDRRTPhosphoSitePlus
S229HKTRKsVYGLQRegPhos
S434LMKSDsYPRFIPKCa(PKC alphaRegPhos
S434LMKSDsYPRFIRGSPhosphoSitePlus
S241DIRSHsPTHTPFlxAPhosphoSitePlus
S323ASKEPsQQRVKPhosphoSitePlus

Dephosphorylation site
RGS7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000355523R33WCOSMICOvarian Cancer21720365
ENSP00000355523F57LCOSMICRenal Cancer20054297
ENSP00000355523L145HCOSMICOvarian Cancer21720365
ENSP00000355523S285RCOSMICOvarian Cancer21720365

Differential expressed protein
RGS7_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RGS7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANRGS7_HUMANkinase -> substrateRegPhos
KPCA_HUMANRGS7_HUMANkinase -> substrateHPRD; Robert H Newman (2013)

Function Annotation
KEGG Pathway
RGS7_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIBAcellular_component
GO:0031681G-protein beta-subunit bindingIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0043547positive regulation of GTPase activityIBAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005886plasma membraneIBAcellular_component
GO:0004871signal transducer activityIEAmolecular_function
GO:0008277regulation of G-protein coupled receptor protein sNASbiological_process
GO:0035556intracellular signal transductionIEAbiological_process
GO:0043234protein complexIEAcellular_component
GO:0008277regulation of G-protein coupled receptor protein sIEAbiological_process
GO:0038032termination of G-protein coupled receptor signalinIEAbiological_process
GO:0044292dendrite terminusIEAcellular_component
GO:0005096GTPase activator activityIBAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005829cytosolIEAcellular_component
GO:0005834heterotrimeric G-protein complexIEAcellular_component


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