Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RGS2_HUMAN
Description:regulator of G-protein signaling 2, 24kDa [Source:HGNC Symbol;Acc:9998]
Location:chr1 q31.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S46WKTRLsYFLQNPRKG1HPRD
T54LQNSStPGKPKPhosphoSitePlus
S64KTGKKsKQQAFPRKG1HPRD
S46WKTRLsYFLQNPKG1/cGK-IphosphoELM
S46WKTRLsYFLQNPhosphoSitePlus
S64KTGKKsKQQAFPKG1/cGK-IphosphoELM
S46WKTRLsYFLQNPKG1RegPhos
S64KTGKKsKQQAFPhosphoSitePlus
S64KTGKKsKQQAFPKG1RegPhos

Dephosphorylation site
RGS2_HUMAN do not have dephosphorylation site.

Mutation site
RGS2_HUMAN do not have mutation site.

Differential expressed protein
RGS2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RGS2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KGP1_HUMANRGS2_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
RGS2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0009898internal side of plasma membraneISScellular_component
GO:0005096GTPase activator activityIBAmolecular_function
GO:0045744negative regulation of G-protein coupled receptor ISSbiological_process
GO:0043407negative regulation of MAP kinase activityISSbiological_process
GO:0010519negative regulation of phospholipase activityIEAbiological_process
GO:0010614negative regulation of cardiac muscle hypertrophyIEAbiological_process
GO:0071877regulation of adrenergic receptor signaling pathwaIEAbiological_process
GO:0007049cell cycleIEAbiological_process
GO:0038032termination of G-protein coupled receptor signalinIEAbiological_process
GO:0005730nucleolusIEAcellular_component
GO:0045744negative regulation of G-protein coupled receptor IEAbiological_process
GO:0010614negative regulation of cardiac muscle hypertrophyISSbiological_process
GO:0043407negative regulation of MAP kinase activityIEAbiological_process
GO:0005739mitochondrionIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0071877regulation of adrenergic receptor signaling pathwaISSbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0010519negative regulation of phospholipase activityISSbiological_process
GO:0005886plasma membraneIBAcellular_component
GO:0005737cytoplasmIBAcellular_component
GO:0005516calmodulin bindingTASmolecular_function
GO:0006417regulation of translationIEAbiological_process
GO:0060452positive regulation of cardiac muscle contractionIEAbiological_process
GO:0055119relaxation of cardiac muscleIEAbiological_process
GO:0008277regulation of G-protein coupled receptor protein sTASbiological_process
GO:0005829cytosolIEAcellular_component
GO:0050873brown fat cell differentiationIEAbiological_process
GO:0060452positive regulation of cardiac muscle contractionISSbiological_process
GO:0055119relaxation of cardiac muscleISSbiological_process
GO:0009898internal side of plasma membraneIEAcellular_component
GO:0043547positive regulation of GTPase activityIBAbiological_process
GO:0060087relaxation of vascular smooth muscleIEAbiological_process
GO:0007283spermatogenesisIEAbiological_process
GO:0005829cytosolISScellular_component


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