Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RGS16_HUMAN
Description:regulator of G-protein signaling 16 [Source:HGNC Symbol;Acc:9997]
Location:chr1 q25.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y168MEKDSyPRFLKRGSPhosphoSitePlus
S195TLSSCsLDEPSHPRD; RegPhos
Y168MEKDSyPRFLKEGFRHPRD; phosphoELM; RegPhos
Y177LKSPAyRDLAAEGFRHPRD; phosphoELM; RegPhos
Y177LKSPAyRDLAARGSPhosphoSitePlus
Y168MEKDSyPRFLKSRCHPRD; phosphoELM; RegPhos
Y177LKSPAyRDLAASrcRegPhos
Y168MEKDSyPRFLKCSKHPRD; RegPhos
Y168MEKDSyPRFLKSrcRegPhos
Y177LKSPAyRDLAASRCphosphoELM
Y177LKSPAyRDLAALynphosphoELM; RegPhos
Y168MEKDSyPRFLKLYNHPRD; RegPhos
Y177LKSPAyRDLAARegPhos
Y177LKSPAyRDLAASrc_groupRegPhos

Dephosphorylation site
RGS16_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000356529*203LCOSMICHepatocellular Carcinoma21822264

Differential expressed protein
RGS16_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RGS16_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EGFR_HUMANRGS16_HUMANkinase -> substrateRegPhos
SRC_HUMANRGS16_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANRGS16_HUMANkinase -> substrateRegPhos
CSK_HUMANRGS16_HUMANkinase -> substrateHPRD; RegPhos
LYN_HUMANRGS16_HUMANkinase -> substrateHPRD; RegPhos; Robert H Newman (2013)

Function Annotation
KEGG Pathway
RGS16_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneIBAcellular_component
GO:0043547positive regulation of GTPase activityIBAbiological_process
GO:0038032termination of G-protein coupled receptor signalinIEAbiological_process
GO:0005096GTPase activator activityIBAmolecular_function
GO:0008277regulation of G-protein coupled receptor protein sTASbiological_process
GO:0005737cytoplasmIBAcellular_component
GO:0005516calmodulin bindingTASmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0007601visual perceptionTASbiological_process


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