| UniProt/SwissProt ID: | RGS10_HUMAN |
| Description: | regulator of G-protein signaling 10 [Source:HGNC Symbol;Acc:9992] |
| Location: | chr10 q26.11 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S16 | RKRPPsDIHDS | HPRD | |
| S162 | AAKRAsRIY | PRKACA | HPRD |
| S176 | YNT | PKA_group | RegPhos |
| S176 | AAKRAsRIY | PRKACA | HPRD |
| S168 | AAKRAsRIY | PKA_group | phosphoELM |
| S16 | HDSDGsSSSSH | phosphoELM | |
| S168 | AAKRAsRIYNT | PKACa | RegPhos |
| Dephosphorylation site |
| RGS10_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000358097 | *174R | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| RGS10_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RGS10_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | RGS10_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| RGS10_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0043547 | positive regulation of GTPase activity | IBA | biological_process |
| GO:0043679 | axon terminus | IEA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0043197 | dendritic spine | IEA | cellular_component |
| GO:0005096 | GTPase activator activity | IBA | molecular_function |
| GO:0038032 | termination of G-protein coupled receptor signalin | IEA | biological_process |
| GO:0043025 | neuronal cell body | IEA | cellular_component |
| GO:0005886 | plasma membrane | IBA | cellular_component |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0005737 | cytoplasm | IBA | cellular_component |