Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RFX3_HUMAN
Description:regulatory factor X, 3 (influences HLA class II expression) [Source:HGNC Symbol;Acc:9984]
Location:chr9 p24.2
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y271QEDMQyMAMRQPhosphoSitePlus
T742RQCSAtGNTYTPhosphoSitePlus
S678GSEVEsEMDEEHPRD
S674DKDEGsEVESEPhosphoSitePlus; HPRD
T395TPTDGtTITESPhosphoSitePlus
T398DGTTItESSNLPhosphoSitePlus

Dephosphorylation site
RFX3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000351574V60MCOSMICHead and Neck Cancer21798893
ENSP00000351574A458GCOSMICPancreatic Cancer
ENSP00000371434A458GBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000351574S178CCOSMICOvarian Cancer21720365
ENSP00000351574E632KCOSMICSkin Cancer21984974
ENSP00000351574P445SCOSMICSkin Cancer21984974
ENSP00000351574M84ICOSMICOvarian Cancer21720365

Differential expressed protein
RFX3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RFX3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RFX3_HUMANDQB1_HUMANTF -> target geneTRANSFAC
RFX3_HUMANDRA_HUMANTF -> target geneTRANSFAC
RFX3_HUMANIL5RA_HUMANTF -> target geneTRANSFAC
RFX3_HUMANDPA1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
RFX3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005667transcription factor complexICcellular_component
GO:0044212transcription regulatory region DNA bindingIEAmolecular_function
GO:0042384cilium assemblyIEAbiological_process
GO:2000078positive regulation of type B pancreatic cell deveIEAbiological_process
GO:0005634nucleusICcellular_component
GO:0007368determination of left/right symmetryIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0050796regulation of insulin secretionIEAbiological_process
GO:0031018endocrine pancreas developmentISSbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0072560type B pancreatic cell maturationIEAbiological_process
GO:0003705RNA polymerase II distal enhancer sequence-specifiTASmolecular_function
GO:0006355regulation of transcription, DNA-dependentISSbiological_process
GO:0031018endocrine pancreas developmentIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0000790nuclear chromatinIEAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0060287epithelial cilium movement involved in determinatiIEAbiological_process
GO:0060285ciliary cell motilityIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0003677DNA bindingTASmolecular_function
GO:0048469cell maturationISSbiological_process
GO:0048469cell maturationIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process


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