| UniProt/SwissProt ID: | RBM19_HUMAN |
| Description: | RNA binding motif protein 19 [Source:HGNC Symbol;Acc:29098] |
| Location: | chr12 q24.21 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T813 | ISERAtKPAVT | PhosphoSitePlus | |
| S677 | LQDTPsEPMEK | PhosphoSitePlus | |
| S194 | LEEEAsLEPKA | HPRD | |
| S167 | KSKPAsDYLNF | HPRD | |
| S845 | PFQAHsREIRE | RRM_1 | PhosphoSitePlus |
| T831 | PRKQTtSKILV | PhosphoSitePlus; HPRD | |
| S832 | RKQTTsKILVR | PhosphoSitePlus; HPRD | |
| T957 | DSEEQtL | HPRD | |
| T818 | TKPAVtLARKK | PhosphoSitePlus | |
| T860 | FGELKtVRLPK | HPRD | |
| S163 | PSKGKsKPASD | HPRD | |
| T479 | HVLPStIKKEA | PhosphoSitePlus | |
| S174 | YLNFDsDSGQE | PhosphoSitePlus; HPRD; phosphoELM | |
| T872 | MTGTGtHRGFG | RRM_1 | PhosphoSitePlus |
| S240 | HCDEGsEAEEE | PhosphoSitePlus | |
| S953 | GSDSDsEEQTL | HPRD | |
| Y169 | KPASDyLNFDS | HPRD | |
| Y433 | LSELHyPIDSL | RRM_1 | PhosphoSitePlus |
| T860 | FGELKtVRLPK | RRM_1 | PhosphoSitePlus |
| S949 | EQLEGsDSDSE | PhosphoSitePlus; HPRD; phosphoELM | |
| T606 | AQLQEtFGHFG | PhosphoSitePlus | |
| Y425 | KLFSKyGPLSE | RRM_1 | PhosphoSitePlus |
| Y356 | KCNREyMGGRY | RRM_1 | PhosphoSitePlus |
| S229 | SEEEEsEDEAV | PhosphoSitePlus | |
| S936 | PKKKRsVVLDE | PhosphoSitePlus | |
| S951 | LEGSDsDSEEQ | PhosphoSitePlus; HPRD; phosphoELM | |
| S180 | DSGQEsEEEGA | PhosphoSitePlus; HPRD; phosphoELM | |
| S176 | NFDSDsGQESE | PhosphoSitePlus; HPRD; phosphoELM | |
| S489 | ASEDAsALGSS | PhosphoSitePlus | |
| Dephosphorylation site |
| RBM19_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000376344 | G555R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000261741 | G555R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000261741 | G492E | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000376344 | E115K | COSMIC | Melanoma | 20016485 | ENSP00000376344 | V661I | COSMIC | Ovarian Cancer | 21720365 | ENSP00000376344 | G492E | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000376344 | A527V | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000376344 | P477L | COSMIC | Hepatocellular Carcinoma |
| Differential expressed protein |
| RBM19_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RBM19_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCA_HUMAN | RBM19_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| RBM19_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005730 | nucleolus | IEA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005730 | nucleolus | ISS | cellular_component |
| GO:0007275 | multicellular organismal development | IEA | biological_process |
| GO:0040019 | positive regulation of embryonic development | ISS | biological_process |
| GO:0040019 | positive regulation of embryonic development | IEA | biological_process |
| GO:0005737 | cytoplasm | ISS | cellular_component |
| GO:0005654 | nucleoplasm | ISS | cellular_component |
| GO:0005654 | nucleoplasm | IEA | cellular_component |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005694 | chromosome | IEA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0000166 | nucleotide binding | IEA | molecular_function |