Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RAB4A_HUMAN
Description:RAB4A, member RAS oncogene family [Source:HGNC Symbol;Acc:9781]
Location:chr1 q42.13
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S199LRQLRsPRRAQCDC2RegPhos
S185PERMGsGIQYGPhosphoSitePlus
Y189GSGIQyGDAALPhosphoSitePlus
T19IGNAGtGKSCLRasPhosphoSitePlus
S199LRQLRsPRRAQPhosphoSitePlus
S199LRQLRsPRRAQCDK_groupphosphoELM; RegPhos
S204LRQLRsPRRAQCDK1HPRD
T132ADREVtFLEASRasPhosphoSitePlus
T24IGNAGtGKSCLHPRD
S137TFLEAsRFAQERasPhosphoSitePlus

Dephosphorylation site
RAB4A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000355651A208TTCGAOvarian Cancer21720365, 18772890
ENSP00000355651A208TCOSMICOvarian Cancer21720365

Differential expressed protein
RAB4A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RAB4A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK1_HUMANRAB4A_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04144Endocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030100regulation of endocytosisIEAbiological_process
GO:0006886intracellular protein transportIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005622intracellularIEAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0007165signal transductionIEAbiological_process
GO:0006913nucleocytoplasmic transportIEAbiological_process
GO:0008565protein transporter activityIEAmolecular_function
GO:0005768endosomeIEAcellular_component
GO:0003924GTPase activityIDAmolecular_function
GO:0005525GTP bindingIDAmolecular_function
GO:0007264small GTPase mediated signal transductionIEAbiological_process
GO:0015031protein transportIEAbiological_process
GO:0019003GDP bindingIDAmolecular_function
GO:0006184GTP catabolic processIDAbiological_process
GO:0016020membraneIEAcellular_component
GO:0005515protein bindingIPImolecular_function


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