Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTN_HUMAN
Description:pleiotrophin [Source:HGNC Symbol;Acc:9630]
Location:chr7 q33
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T134AECQKtVTISKPTN_MK_CPhosphoSitePlus
T113ECDLNtALKTRPTN_MK_CPhosphoSitePlus
Y101GAECKyQFQAWPTN_MK_CPhosphoSitePlus

Dephosphorylation site
PTN_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000341170A97VBIOMARTBreast Cancer21930507, 21930502
ENSP00000341170E75QCOSMICHead and Neck Cancer21798897
ENSP00000341170K40ICOSMICSkin Cancer21984974

Differential expressed protein
PTN_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTN_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTN_HUMANPTPRZ_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
PTN_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004864protein phosphatase inhibitor activityTASmolecular_function
GO:0007399nervous system developmentTASbiological_process
GO:0005783endoplasmic reticulumIDAcellular_component
GO:0030282bone mineralizationIEAbiological_process
GO:0001503ossificationIEAbiological_process
GO:0051781positive regulation of cell divisionIEAbiological_process
GO:0007185transmembrane receptor protein tyrosine phosphatasTASbiological_process
GO:0008201heparin bindingIEAmolecular_function
GO:0005615extracellular spaceTAScellular_component
GO:0008083growth factor activityIEAmolecular_function
GO:0007612learningIEAbiological_process
GO:0008284positive regulation of cell proliferationTASbiological_process


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