Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTN13_HUMAN
Description:protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) [Source:HGNC Symbol;Acc:9646]
Location:chr4 q21.3
Node attribute:phosphotase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S1824QDPAKsDGRLKPDZPhosphoSitePlus
S2383DHDTPsQPDDLHPRD
S897NLQAEsVRGFNPhosphoSitePlus
S1024TKLNNsKSVASPhosphoSitePlus
S911AISTGsLASSTPhosphoSitePlus; HPRD
S895WSIVSsPEREIHPRD
S240KGLSKsMGFLSPhosphoSitePlus
T508LYPGDtIKASMPhosphoSitePlus
Y2249KNILPyDATRVY_phosphatasePhosphoSitePlus
S1358FKTFSsSPPKPPhosphoSitePlus
T335TVRTStTPRKKPhosphoSitePlus
S130GDHLNsILLGMPhosphoSitePlus
S890RASFRsLNLQAPhosphoSitePlus; HPRD
S2364DHDTPsQPDDLHPRD
S1514SGLGFsFSREDPDZPhosphoSitePlus
S214LPTGRsSTSDVPhosphoSitePlus
S1495SGLGFsFSREDHPRD
S1187ISKVPsTPVHLPhosphoSitePlus
S938KRLSCsELSLYPhosphoSitePlus
S1067WSIVSsPEREIHPRD
Y2375LTFISyMRHIHHPRD
S1026LNNSKsVASLNPhosphoSitePlus
S2398LLTFIsYMRHIHPRD
S1519SGLGFsFSREDHPRD
S1566SLKGLsQQEVIPDZPhosphoSitePlus
S442SKRFEsSSGLPPhosphoSitePlus
S2393LLTFIsYMRHIHPRD
S2202LLTFIsYMRHIHPRD
S2374LLTFIsYMRHIHPRD
Y504SRLSLyPGDTIPhosphoSitePlus
S2032YQIKGsPNLTLPhosphoSitePlus
S2192DHDTPsQPDDLHPRD
T1577SALRGtAPEVFPDZPhosphoSitePlus
S1610VEQSTsSDENEHPRD
S1029SKSVAsLNRSPPhosphoSitePlus
S1343KQESSsSVNTSPhosphoSitePlus
S1086WSIVSsPEREIPhosphoSitePlus; HPRD
S839TLQNTsDGIKHFERM_CPhosphoSitePlus
S502RQSRLsLYPGDPhosphoSitePlus
Y943SELSLyQPLQNPhosphoSitePlus
S829KKISFsKKKITFERM_CPhosphoSitePlus
T838ITLQNtSDGIKFERM_CPhosphoSitePlus
S2388DHDTPsQPDDLHPRD
Y2394LTFISyMRHIHHPRD
T528EIALEtAMTQRPhosphoSitePlus
S914TGSLAsSTLNKPhosphoSitePlus
S1033ASLNRsPERRKPhosphoSitePlus
S1041RRKHEsDSSSIPhosphoSitePlus
S1438VEQSTsSDENEHPRD
S908MGRAIsTGSLAPhosphoSitePlus; HPRD
Y2399LTFISyMRHIHHPRD
S345KEARYsDGSIAPhosphoSitePlus
S1082LHKRWsIVSSPPhosphoSitePlus; phosphoELM
S969REMSKsYHDLSPhosphoSitePlus
S915GSLASsTLNKLPhosphoSitePlus
T1355KMNFKtFSSSPPhosphoSitePlus
T1188SKVPStPVHLTPhosphoSitePlus
S1323SGLGFsFSREDHPRD
S1634VEQSTsSDENEHPRD
T909GRAIStGSLASPhosphoSitePlus
T916SLASStLNKLAPhosphoSitePlus
Y2203LTFISyMRHIHHPRD
S936ILKRLsCSELSPhosphoSitePlus
S1629VEQSTsSDENEHPRD
S1514SGLGFsFSREDHPRD

Dephosphorylation site
PTN13_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000394794A880GCOSMICHead and Neck Cancer21798893
ENSP00000394794T673ICOSMICOvarian Cancer21720365
ENSP00000394794T838IBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000408368Q1693EBIOMARTBreast Cancer21930507, 21930502
ENSP00000426626N1525SCOSMICMelanoma19074898
ENSP00000394794S1754LCOSMICMelanoma19074898
ENSP00000408368D2416NBIOMARTBreast Cancer21930507, 21930502
ENSP00000426626T2422NCOSMICOvarian Cancer21720365
ENSP00000394794T2422NCOSMICOvarian Cancer21720365
ENSP00000407249Q1712EBIOMARTBreast Cancer21930507, 21930502
ENSP00000426626I1527MCOSMICMelanoma19074898
ENSP00000407249Q2228HBIOMARTBreast Cancer21930507, 21930502
ENSP00000394794N1525SCOSMICMelanoma19074898
ENSP00000408368I2373TTCGAOvarian Cancer21720365, 18772890
ENSP00000394794I1175MCOSMICOvarian Cancer21720365
ENSP00000426626Q2233HBIOMARTBreast Cancer21930507, 21930502
ENSP00000426626T673ICOSMICOvarian Cancer21720365
ENSP00000426626S1754LCOSMICMelanoma19074898
ENSP00000322675Q1521EBIOMARTBreast Cancer21930507, 21930502
ENSP00000394794Q2467LCOSMICMelanoma19074898
ENSP00000426626I1175MCOSMICOvarian Cancer21720365
ENSP00000408368T673ITCGAOvarian Cancer21720365, 18772890
ENSP00000407249D2435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000408368Q2209HBIOMARTBreast Cancer21930507, 21930502
ENSP00000426626D2440NBIOMARTBreast Cancer21930507, 21930502
ENSP00000394794Q1717EBIOMARTBreast Cancer21930507, 21930502
ENSP00000394794R1522*COSMICMelanoma19074898
ENSP00000322675D2244NBIOMARTBreast Cancer21930507, 21930502
ENSP00000426626Q1717EBIOMARTBreast Cancer21930507, 21930502
ENSP00000322675Q2037HBIOMARTBreast Cancer21930507, 21930502
ENSP00000408368T2398NTCGAOvarian Cancer21720365, 18772890
ENSP00000426626R1522*COSMICMelanoma19074898
ENSP00000394794I1527MCOSMICMelanoma19074898
ENSP00000426626Q2467LCOSMICMelanoma19074898
ENSP00000426626I2373TCOSMICOvarian Cancer21720365
ENSP00000394794D2440NBIOMARTBreast Cancer21930507, 21930502
ENSP00000394794I2373TCOSMICOvarian Cancer21720365
ENSP00000394794Q2233HBIOMARTBreast Cancer21930507, 21930502
ENSP00000426626A880GCOSMICHead and Neck Cancer21798893

Differential expressed protein
PTN13_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTN13_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTN13_HUMANIKBA_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
PTN13_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006470protein dephosphorylationTASbiological_process
GO:0016791phosphatase activityIEAmolecular_function
GO:0030027lamellipodiumIDAcellular_component
GO:0004725protein tyrosine phosphatase activityIDAmolecular_function
GO:0035335peptidyl-tyrosine dephosphorylationIDAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0016311dephosphorylationIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005856cytoskeletonIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component


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