| UniProt/SwissProt ID: | PTMA_HUMAN |
| Description: | prothymosin, alpha [Source:HGNC Symbol;Acc:9623] |
| Location: | chr2 q37.1 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T106 | TKKQKtDE | HPRD | |
| T13 | TSSEItTKDLK | Prothymosin | PhosphoSitePlus |
| S2 | ____MsDAAVD | Prothymosin | PhosphoSitePlus |
| T8 | DAAVDtSSEIT | Prothymosin | PhosphoSitePlus |
| S2 | AAVD | HPRD; phosphoELM | |
| S10 | AVDTSsEITTK | Prothymosin | PhosphoSitePlus |
| T107 | TKKQKtDEDD_ | Prothymosin | PhosphoSitePlus |
| T14 | SSEITtKDLKE | HPRD | |
| T13 | TSSEItTKDLK | HPRD | |
| T8 | DAAVDtSSEIT | HPRD; phosphoELM | |
| T107 | TKKQKtDE | HPRD | |
| T86 | EAESAtGKRAA | HPRD | |
| T8 | DAAVDtSSEIT | CK2_group | phosphoELM |
| T102 | DDDVDtKKQKT | HPRD | |
| T13 | TSSEItTKDLK | CK2_group | phosphoELM |
| S10 | AVDTSsEITTK | HPRD | |
| S9 | AAVDTsSEITT | HPRD | |
| T102 | DDDVDtKKQKT | Prothymosin | PhosphoSitePlus |
| S9 | AAVDTsSEITT | Prothymosin | PhosphoSitePlus |
| T14 | SSEITtKDLKE | CK2_group | phosphoELM |
| T101 | DDDVDtKKQKT | HPRD | |
| Dephosphorylation site |
| PTMA_HUMAN do not have dephosphorylation site. |
| Mutation site |
| PTMA_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000344547 | Oral Premalignant Lesions | Normal vs. Cancer | tissue | Down | 0.64 | 19072117 | ENSP00000344547 | Oral Premalignant Lesions | Normal vs. Cancer | tissue | Down | 0.61 | 19072117 | ENSP00000344547 | Oral Premalignant Lesions | Normal vs. Cancer | tissue | Up | 1.2 | 19072117 | ENSP00000344547 | Oral Premalignant Lesions | Normal vs. Cancer | tissue | Up | 1.5 | 19072117 | ENSP00000344547 | Oral Premalignant Lesions | Normal vs. Cancer | tissue | Up | 3.9 | 19072117 | ENSP00000344547 | Oral Premalignant Lesions | Normal vs. Cancer | tissue | Up | 3.5 | 19072117 | ENSP00000344547 | Lung Cancer | Treatment (none vs transfected with pc3.1-hPNAS5) | cell line | Down | 19795389 |
| Hyperphosphorylation site |
| PTMA_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ESR1_HUMAN | PTMA_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| PTMA_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006351 | transcription, DNA-dependent | TAS | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |