| UniProt/SwissProt ID: | PROK1_HUMAN |
| Description: | prokineticin 1 [Source:HGNC Symbol;Acc:18454] |
| Location: | chr1 p13.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T23 | DCAVItGACER | Prokineticin | PhosphoSitePlus |
| S17 | LLVTVsDCAVI | Prokineticin | PhosphoSitePlus |
| S8 | GATRVsIMLLL | Prokineticin | PhosphoSitePlus |
| Dephosphorylation site |
| PROK1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000271331 | *106C | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| PROK1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PROK1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PROK1_HUMAN | PKR1_HUMAN | ligand -> receptor | HPMR |
| PROK1_HUMAN | PKR2_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| PROK1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0001525 | angiogenesis | IEA | biological_process |
| GO:0008083 | growth factor activity | IEA | molecular_function |
| GO:0051781 | positive regulation of cell division | IEA | biological_process |
| GO:0005576 | extracellular region | IEA | cellular_component |
| GO:0045765 | regulation of angiogenesis | IEA | biological_process |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0008284 | positive regulation of cell proliferation | IEA | biological_process |
| GO:0000187 | activation of MAPK activity | IEA | biological_process |