| UniProt/SwissProt ID: | PKR1_HUMAN |
| Description: | prokineticin receptor 1 [Source:HGNC Symbol;Acc:4524] |
| Location: | chr2 p13.3 |
| Node attribute: | receptor |
| Phosphorylation site |
| PKR1_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| PKR1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000377874 | I379V | BIOMART | Gastric Cancer | 21930507, 21930502 | ENSP00000377874 | M332R | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000303775 | D224Y | BIOMART | Hepatocellular Carcinoma | 21930507, 21930502 | ENSP00000303775 | M332R | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000303775 | M332R | COSMIC | Ovarian Cancer | 21720365 | ENSP00000303775 | H26Y | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| PKR1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PKR1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PROK1_HUMAN | PKR1_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| PKR1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0043066 | negative regulation of apoptotic process | IEA | biological_process |
| GO:0004983 | neuropeptide Y receptor activity | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |