Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PPAP_HUMAN
Description:acid phosphatase, prostate [Source:HGNC Symbol;Acc:125]
Location:chr3 q22.1
Node attribute:phosphotase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T171ELESEtLKSEEAcid_phosphat_APhosphoSitePlus
T233TEDTMtKLRELAcid_phosphat_APhosphoSitePlus
S239KLRELsELSLLAcid_phosphat_APhosphoSitePlus
T231WATEDtMTKLRAcid_phosphat_APhosphoSitePlus

Dephosphorylation site
PPAP_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000337471C372FCOSMICOvarian Cancer21720365
ENSP00000337471C372FTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000337471Prostate CancerMetastasistissueDown0.4218553995

Hyperphosphorylation site
PPAP_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PPAP_HUMANERBB2_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa00740Riboflavin metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005576extracellular regionIEAcellular_component
GO:0016311dephosphorylationIEAbiological_process
GO:0042802identical protein bindingIPImolecular_function
GO:0005886plasma membraneIDAcellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0045177apical part of cellIEAcellular_component
GO:0005771multivesicular bodyIEAcellular_component
GO:0031985Golgi cisternaIEAcellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0046085adenosine metabolic processIEAbiological_process
GO:0006144purine nucleobase metabolic processIEAbiological_process
GO:0003993acid phosphatase activityIEAmolecular_function
GO:0033265choline bindingIEAmolecular_function
GO:00082535'-nucleotidase activityIEAmolecular_function
GO:0005765lysosomal membraneIEAcellular_component
GO:0030175filopodiumIEAcellular_component
GO:0030141secretory granuleIEAcellular_component
GO:0009117nucleotide metabolic processIEAbiological_process
GO:0005622intracellularIDAcellular_component


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