Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PPA5_HUMAN
Description:acid phosphatase 5, tartrate resistant [Source:HGNC Symbol;Acc:124]
Location:chr19 p13.2
Node attribute:phosphotase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y283YLRFHyGTEDSPhosphoSitePlus
Y278KVPNGyLRFHYPhosphoSitePlus

Dephosphorylation site
PPA5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000218758W34*COSMICCentral Nervous System Neoplasms18772396
ENSP00000413456W34*BIOMARTNeoplasms by Histologic Type21930507, 21930502

Differential expressed protein
PPA5_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PPA5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PPA5_HUMANOSTP_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05323Rheumatoid arthritis
hsa04380Osteoclast differentiation
hsa04142Lysosome
hsa00740Riboflavin metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008198ferrous iron bindingIDAmolecular_function
GO:0005764lysosomeIEAcellular_component
GO:0016021integral to membraneTAScellular_component
GO:0003993acid phosphatase activityTASmolecular_function
GO:0008199ferric iron bindingIDAmolecular_function
GO:0016787hydrolase activityIEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0006766vitamin metabolic processTASbiological_process
GO:0006771riboflavin metabolic processTASbiological_process
GO:0006767water-soluble vitamin metabolic processTASbiological_process
GO:0005829cytosolTAScellular_component


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