| UniProt/SwissProt ID: | PPA5_HUMAN |
| Description: | acid phosphatase 5, tartrate resistant [Source:HGNC Symbol;Acc:124] |
| Location: | chr19 p13.2 |
| Node attribute: | phosphotase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y283 | YLRFHyGTEDS | PhosphoSitePlus | |
| Y278 | KVPNGyLRFHY | PhosphoSitePlus | |
| Dephosphorylation site |
| PPA5_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000218758 | W34* | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000413456 | W34* | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 |
| Differential expressed protein |
| PPA5_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PPA5_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PPA5_HUMAN | OSTP_HUMAN | phosphatase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05323 | Rheumatoid arthritis |
| hsa04380 | Osteoclast differentiation |
| hsa04142 | Lysosome |
| hsa00740 | Riboflavin metabolism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0008198 | ferrous iron binding | IDA | molecular_function |
| GO:0005764 | lysosome | IEA | cellular_component |
| GO:0016021 | integral to membrane | TAS | cellular_component |
| GO:0003993 | acid phosphatase activity | TAS | molecular_function |
| GO:0008199 | ferric iron binding | IDA | molecular_function |
| GO:0016787 | hydrolase activity | IEA | molecular_function |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0006766 | vitamin metabolic process | TAS | biological_process |
| GO:0006771 | riboflavin metabolic process | TAS | biological_process |
| GO:0006767 | water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |