Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PLIN1_HUMAN
Description:perilipin 1 [Source:HGNC Symbol;Acc:9076]
Location:chr15 q26.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y58SVCNAyEKGVQPerilipinPhosphoSitePlus
Y401DTVVHyVPLPRPhosphoSitePlus
T301EDQTDtEGEDTPerilipinPhosphoSitePlus
T299DHEDQtDTEGEPerilipinPhosphoSitePlus
S81VVRRLsTQFTAPerilipinPhosphoSitePlus
S384RAMSLsDALKGPerilipinPhosphoSitePlus
S53HPLVAsVCNAYPerilipinPhosphoSitePlus
T40ECFQKtYTSTKPerilipinPhosphoSitePlus
S81VVRRLsTQFTAPRKACAHPRD
S382KGRAMsLSDALPerilipinPhosphoSitePlus
T306TEGEDtEEEEEPerilipinPhosphoSitePlus
Y515LGRTHySQLRKPhosphoSitePlus

Dephosphorylation site
PLIN1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000300055L191RCOSMICMelanoma20016485
ENSP00000300055E162KCOSMICSkin Cancer21984974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000402167Breast CancerMetastasistissueDown0.4119053527
ENSP00000402167Breast CancerMetastasistissueDown0.4219053527

Hyperphosphorylation site
PLIN1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANPLIN1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03320PPAR signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019433triglyceride catabolic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0006629lipid metabolic processNASbiological_process
GO:0008289lipid bindingNASmolecular_function
GO:0016042lipid catabolic processIEAbiological_process
GO:0005811lipid particleNAScellular_component


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