Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PLF4_HUMAN
Description:platelet factor 4 [Source:HGNC Symbol;Acc:8861]
Location:chr4 q13.3
Node attribute:ligand

Phosphorylation site
PLF4_HUMAN do not have phosphorylation site.

Dephosphorylation site
PLF4_HUMAN do not have dephosphorylation site.

Mutation site
PLF4_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000296029acute lymphocytic leukemiaNormal vs. CancertissueDown19291297

Hyperphosphorylation site
PLF4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PLF4_HUMANLDLR_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04060Cytokine-cytokine receptor interaction
hsa04062Chemokine signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045653negative regulation of megakaryocyte differentiatiIDAbiological_process
GO:0045347negative regulation of MHC class II biosynthetic pIDAbiological_process
GO:0043066negative regulation of apoptotic processIDAbiological_process
GO:0016525negative regulation of angiogenesisIDAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0002576platelet degranulationTASbiological_process
GO:0006955immune responseIEAbiological_process
GO:0045918negative regulation of cytolysisIDAbiological_process
GO:0031093platelet alpha granule lumenTAScellular_component
GO:0019221cytokine-mediated signaling pathwayIDAbiological_process
GO:0045651positive regulation of macrophage differentiationIDAbiological_process
GO:0032760positive regulation of tumor necrosis factor produIDAbiological_process
GO:0030168platelet activationIDAbiological_process
GO:0010628positive regulation of gene expressionIDAbiological_process
GO:0010744positive regulation of macrophage derived foam celIDAbiological_process
GO:0005576extracellular regionICcellular_component
GO:0008009chemokine activityTASmolecular_function
GO:0030595leukocyte chemotaxisIDAbiological_process
GO:0008201heparin bindingIDAmolecular_function
GO:0005615extracellular spaceIEAcellular_component


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