| UniProt/SwissProt ID: | PLAL2_HUMAN |
| Description: | pleiomorphic adenoma gene-like 2 [Source:HGNC Symbol;Acc:9047] |
| Location: | chr20 q11.21 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S241 | RHVKKsHSQEL | zf-C2H2 | PhosphoSitePlus |
| T251 | LLKIKtEPVDM | PhosphoSitePlus | |
| T265 | LSCSStVSVKE | PhosphoSitePlus | |
| Dephosphorylation site |
| PLAL2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000246229 | A80V | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| PLAL2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PLAL2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| AURKC_HUMAN | PLAL2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| PLAL2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003700 | sequence-specific DNA binding transcription factor | TAS | molecular_function |
| GO:0006629 | lipid metabolic process | IEA | biological_process |
| GO:0001077 | RNA polymerase II core promoter proximal region se | IDA | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
| GO:0034378 | chylomicron assembly | IEA | biological_process |
| GO:0043565 | sequence-specific DNA binding | IDA | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0009791 | post-embryonic development | IEA | biological_process |
| GO:0006917 | induction of apoptosis | IEA | biological_process |