| UniProt/SwissProt ID: | PKHO2_HUMAN |
| Description: | pleckstrin homology domain containing, family O member 2 [Source:HGNC Symbol;Acc:30026] |
| Location: | chr15 q22.31 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S256 | PAEEDsGSEQP | PhosphoSitePlus; HPRD | |
| S420 | EVKVAsEQTEK | PhosphoSitePlus | |
| S390 | HPRCSsLGDLL | PhosphoSitePlus; HPRD | |
| S468 | DLGELsQEAPG | PhosphoSitePlus; HPRD | |
| S389 | FHPRCsSLGDL | PhosphoSitePlus; HPRD | |
| S29 | WIKKSsGGLLG | PH | PhosphoSitePlus |
| S28 | GWIKKsSGGLL | PH | PhosphoSitePlus |
| Dephosphorylation site |
| PKHO2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000326706 | P386S | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000326706 | E359K | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| PKHO2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PKHO2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PKHO2_HUMAN | PGFRB_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005543 | phospholipid binding | IEA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |