Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PITX1_HUMAN
Description:paired-like homeodomain 1 [Source:HGNC Symbol;Acc:9004]
Location:chr5 q31.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S314ACQYHPRD
S48LENSAsESSDTPhosphoSitePlus; HPRD; phosphoELM
S50NSASEsSDTELHPRD; phosphoELM
S51SASESsDTELPHPRD; phosphoELM
S284NSSLAsLRLKSOARPhosphoSitePlus
T53SESSDtELPEKHPRD
S46EPLENsASESSPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
PITX1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265340V273ICOSMICOvarian Cancer21720365
ENSP00000427542V273ICOSMICOvarian Cancer21720365

Differential expressed protein
PITX1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PITX1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FASTK_HUMANPITX1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PITX1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0014707branchiomeric skeletal muscle developmentIEAbiological_process
GO:0005730nucleolusIDAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0005667transcription factor complexIEAcellular_component
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0009653anatomical structure morphogenesisTASbiological_process
GO:0035116embryonic hindlimb morphogenesisIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0035137hindlimb morphogenesisIEAbiological_process
GO:0051216cartilage developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0001501skeletal system developmentIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0001501skeletal system developmentTASbiological_process
GO:0021983pituitary gland developmentIEAbiological_process
GO:0048625myoblast cell fate commitmentIEAbiological_process
GO:0000988protein binding transcription factor activityIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process


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