Phosphorylation

Protein information

UniProt/SwissProt ID:	PITX1_HUMAN
Description:	paired-like homeodomain 1 [Source:HGNC Symbol;Acc:9004]
Location:	chr5 q31.1
Node attribute:	substrate

Position	PhosphoPeptide	Catalytic kinase	Source
S314	ACQY		HPRD
S48	LENSAsESSDT		PhosphoSitePlus; HPRD; phosphoELM
S50	NSASEsSDTEL		HPRD; phosphoELM
S51	SASESsDTELP		HPRD; phosphoELM
S284	NSSLAsLRLKS	OAR	PhosphoSitePlus
T53	SESSDtELPEK		HPRD
S46	EPLENsASESS		PhosphoSitePlus; HPRD; phosphoELM

PITX1_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000265340	V273I	COSMIC	Ovarian Cancer	21720365
ENSP00000427542	V273I	COSMIC	Ovarian Cancer	21720365

PITX1_HUMAN is not differential expressed protein.

PITX1_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
FASTK_HUMAN	PITX1_HUMAN	kinase -> substrate	Robert H Newman (2013)

KEGG Pathway

PITX1_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0014707	branchiomeric skeletal muscle development	IEA	biological_process
GO:0005730	nucleolus	IDA	cellular_component
GO:0003677	DNA binding	IEA	molecular_function
GO:0005667	transcription factor complex	IEA	cellular_component
GO:0043565	sequence-specific DNA binding	IEA	molecular_function
GO:0009653	anatomical structure morphogenesis	TAS	biological_process
GO:0035116	embryonic hindlimb morphogenesis	IEA	biological_process
GO:0005737	cytoplasm	IEA	cellular_component
GO:0035137	hindlimb morphogenesis	IEA	biological_process
GO:0051216	cartilage development	IEA	biological_process
GO:0005634	nucleus	IEA	cellular_component
GO:0001501	skeletal system development	IEA	biological_process
GO:0003700	sequence-specific DNA binding transcription factor	IEA	molecular_function
GO:0006355	regulation of transcription, DNA-dependent	IEA	biological_process
GO:0045944	positive regulation of transcription from RNA poly	IEA	biological_process
GO:0001501	skeletal system development	TAS	biological_process
GO:0021983	pituitary gland development	IEA	biological_process
GO:0048625	myoblast cell fate commitment	IEA	biological_process
GO:0000988	protein binding transcription factor activity	IEA	molecular_function
GO:0006351	transcription, DNA-dependent	IEA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network