Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PITM1_HUMAN
Description:phosphatidylinositol transfer protein, membrane-associated 1 [Source:HGNC Symbol;Acc:9003]
Location:chr11 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T1223REGPGtPPTTLErk2(MAPK1RegPhos
S600NNELLsPEFGPPhosphoSitePlus; HPRD; RegPhos
T287ASNTGtPDGPECDC2RegPhos
T287ASNTGtPDGPECDC2(CDK1RegPhos
T1223REGPGtPPTTLMAPK1phosphoELM
S382IDAFAsPVEAECDC2(CDK1RegPhos
S509DSLSRsQDHIPPhosphoSitePlus
T1020VVARGtEAVVFPhosphoSitePlus
S382IDAFAsPVEAECDC2RegPhos
S896EPSIYsPAFPRPhosphoSitePlus; phosphoELM; RegPhos
T287ASNTGtPDGPECDK1phosphoELM
S936RPQVLsGRFMYPhosphoSitePlus
T794MLVPStPTSTSErk2(MAPK1RegPhos
T794MLVPStPTSTSDDHDPhosphoSitePlus
T59GSGQYtHKVYHIP_transPhosphoSitePlus
S300PGPDAsPDASFRegPhos
T1223REGPGtPPTTLPhosphoSitePlus
S382IDAFAsPVEAEPhosphoSitePlus
T59GSGQYtHKVYHRegPhos
S638PSDMAsPEPEGPhosphoSitePlus; phosphoELM; RegPhos
T389VEAEGtPEPGAPhosphoSitePlus; phosphoELM; RegPhos
T287ASNTGtPDGPEPhosphoSitePlus
S1214RSRGPsQAEREPhosphoSitePlus
T794MLVPStPTSTSMAPK1phosphoELM
S621GLGRGsPEPSAPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S382IDAFAsPVEAECDK1phosphoELM
S593SSRRGsMNNELPhosphoSitePlus; HPRD; RegPhos

Dephosphorylation site
PITM1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000348772T389MCOSMICCentral Nervous System Neoplasms18772396
ENSP00000437286T389MCOSMICCentral Nervous System Neoplasms18772396
ENSP00000348772T539ICOSMICSkin Cancer21984974
ENSP00000437286T539ICOSMICSkin Cancer21984974

Differential expressed protein
PITM1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PITM1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK01_HUMANPITM1_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANPITM1_HUMANkinase -> substrateRegPhos
CDK1_HUMANPITM1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
PITM1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006810transportIEAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0030496midbodyIEAcellular_component
GO:0015031protein transportIEAbiological_process
GO:0016020membraneTAScellular_component
GO:0007602phototransductionTASbiological_process
GO:0005811lipid particleIEAcellular_component
GO:0032154cleavage furrowIEAcellular_component
GO:0006629lipid metabolic processNASbiological_process
GO:0005789endoplasmic reticulum membraneIEAcellular_component
GO:0032580Golgi cisterna membraneIEAcellular_component
GO:0008526phosphatidylinositol transporter activityTASmolecular_function
GO:0007420brain developmentTASbiological_process


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