| UniProt/SwissProt ID: | PITM1_HUMAN |
| Description: | phosphatidylinositol transfer protein, membrane-associated 1 [Source:HGNC Symbol;Acc:9003] |
| Location: | chr11 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T1223 | REGPGtPPTTL | Erk2(MAPK1 | RegPhos |
| S600 | NNELLsPEFGP | PhosphoSitePlus; HPRD; RegPhos | |
| T287 | ASNTGtPDGPE | CDC2 | RegPhos |
| T287 | ASNTGtPDGPE | CDC2(CDK1 | RegPhos |
| T1223 | REGPGtPPTTL | MAPK1 | phosphoELM |
| S382 | IDAFAsPVEAE | CDC2(CDK1 | RegPhos |
| S509 | DSLSRsQDHIP | PhosphoSitePlus | |
| T1020 | VVARGtEAVVF | PhosphoSitePlus | |
| S382 | IDAFAsPVEAE | CDC2 | RegPhos |
| S896 | EPSIYsPAFPR | PhosphoSitePlus; phosphoELM; RegPhos | |
| T287 | ASNTGtPDGPE | CDK1 | phosphoELM |
| S936 | RPQVLsGRFMY | PhosphoSitePlus | |
| T794 | MLVPStPTSTS | Erk2(MAPK1 | RegPhos |
| T794 | MLVPStPTSTS | DDHD | PhosphoSitePlus |
| T59 | GSGQYtHKVYH | IP_trans | PhosphoSitePlus |
| S300 | PGPDAsPDASF | RegPhos | |
| T1223 | REGPGtPPTTL | PhosphoSitePlus | |
| S382 | IDAFAsPVEAE | PhosphoSitePlus | |
| T59 | GSGQYtHKVYH | RegPhos | |
| S638 | PSDMAsPEPEG | PhosphoSitePlus; phosphoELM; RegPhos | |
| T389 | VEAEGtPEPGA | PhosphoSitePlus; phosphoELM; RegPhos | |
| T287 | ASNTGtPDGPE | PhosphoSitePlus | |
| S1214 | RSRGPsQAERE | PhosphoSitePlus | |
| T794 | MLVPStPTSTS | MAPK1 | phosphoELM |
| S621 | GLGRGsPEPSA | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| S382 | IDAFAsPVEAE | CDK1 | phosphoELM |
| S593 | SSRRGsMNNEL | PhosphoSitePlus; HPRD; RegPhos | |
| Dephosphorylation site |
| PITM1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000348772 | T389M | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000437286 | T389M | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000348772 | T539I | COSMIC | Skin Cancer | 21984974 | ENSP00000437286 | T539I | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| PITM1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PITM1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK01_HUMAN | PITM1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ZAGL2_HUMAN | PITM1_HUMAN | kinase -> substrate | RegPhos |
| CDK1_HUMAN | PITM1_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| PITM1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006810 | transport | IEA | biological_process |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0030496 | midbody | IEA | cellular_component |
| GO:0015031 | protein transport | IEA | biological_process |
| GO:0016020 | membrane | TAS | cellular_component |
| GO:0007602 | phototransduction | TAS | biological_process |
| GO:0005811 | lipid particle | IEA | cellular_component |
| GO:0032154 | cleavage furrow | IEA | cellular_component |
| GO:0006629 | lipid metabolic process | NAS | biological_process |
| GO:0005789 | endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0032580 | Golgi cisterna membrane | IEA | cellular_component |
| GO:0008526 | phosphatidylinositol transporter activity | TAS | molecular_function |
| GO:0007420 | brain development | TAS | biological_process |