Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PIT1_HUMAN
Description:POU class 1 homeobox 1 [Source:HGNC Symbol;Acc:9210]
Location:chr3 p11.2
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T219KRKRRtTISIALsr2; HomeoboxPhosphoSitePlus

Dephosphorylation site
PIT1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000263781T11ICOSMICMelanoma
ENSP00000263781R217QCOSMICSkin Cancer21984974

Differential expressed protein
PIT1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PIT1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PIT1_HUMANSOMA_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
PIT1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0008285negative regulation of cell proliferationTASbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0060133somatotropin secreting cell developmentIEAbiological_process
GO:0021983pituitary gland developmentIEAbiological_process
GO:0003682chromatin bindingIEAmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0003714transcription corepressor activityIEAmolecular_function
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0001105RNA polymerase II transcription coactivator activiIDAmolecular_function
GO:0021984adenohypophysis developmentIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function
GO:0001077RNA polymerase II core promoter proximal region seIEAmolecular_function
GO:0001708cell fate specificationIEAbiological_process
GO:0008340determination of adult lifespanIEAbiological_process
GO:0030183B cell differentiationIEAbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0043567regulation of insulin-like growth factor receptor IEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0008134transcription factor bindingIEAmolecular_function
GO:0001102RNA polymerase II activating transcription factor IPImolecular_function
GO:0040018positive regulation of multicellular organism growIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0032962positive regulation of inositol trisphosphate biosIEAbiological_process
GO:0051169nuclear transportIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0060126somatotropin secreting cell differentiationIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0005737cytoplasmIDAcellular_component