Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PIPNA_HUMAN
Description:phosphatidylinositol transfer protein, alpha [Source:HGNC Symbol;Acc:9001]
Location:chr17 p13.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y57GEKGQyTHKIYphosphoELM
T58EKGQYtHKIYHIP_transPhosphoSitePlus
Y93WNAYPyCRTVIIP_transPhosphoSitePlus
Y140HVEAVyIDIADIP_transPhosphoSitePlus
S165PAKFKsIKTGRPKCa(PKC alphaRegPhos
S165PAKFKsIKTGRPKC_alphaphosphoELM
S165PAKFKsIKTGRIP_transPhosphoSitePlus
Y57GEKGQyTHKIYIP_transPhosphoSitePlus

Dephosphorylation site
PIPNA_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000316809V136MCOSMICOvarian Cancer21720365
ENSP00000316809V136MCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000316809colorectal cancerNormal vs. CancertissueDown0.7419098285
ENSP00000316809Uterine CancerNormal vs. CancertissueUp16051329
ENSP00000316809Uterine CancerNormal vs. CancertissueUp19771267

Hyperphosphorylation site
PIPNA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANPIPNA_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PIPNA_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0015914phospholipid transportIEAbiological_process
GO:0008526phosphatidylinositol transporter activityTASmolecular_function
GO:0006810transportIEAbiological_process
GO:0007601visual perceptionTASbiological_process
GO:0000062fatty-acyl-CoA bindingIEAmolecular_function
GO:0005543phospholipid bindingIEAmolecular_function
GO:0007411axon guidanceTASbiological_process
GO:0035091phosphatidylinositol bindingIEAmolecular_function
GO:0008525phosphatidylcholine transporter activityTASmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0006629lipid metabolic processNASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0070540stearic acid bindingIEAmolecular_function


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