Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PFD5_HUMAN
Description:prefoldin subunit 5 [Source:HGNC Symbol;Acc:8869]
Location:chr12 q13.13
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y90DVGTGyYVEKTPrefoldinPhosphoSitePlus
Y91VGTGYyVEKTAPrefoldinPhosphoSitePlus
Y71LTSSMyVPGKLPrefoldinPhosphoSitePlus

Dephosphorylation site
PFD5_HUMAN do not have dephosphorylation site.

Mutation site
PFD5_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000334188Non-small cell lung carcinomaMetastasiscell lineDown17537172

Hyperphosphorylation site
PFD5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK11_HUMANPFD5_HUMANkinase -> substrateRobert H Newman (2013)
STK16_HUMANPFD5_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PFD5_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0090090negative regulation of canonical Wnt receptor signIMPbiological_process
GO:0006355regulation of transcription, DNA-dependentTASbiological_process
GO:0060041retina development in camera-type eyeIEAbiological_process
GO:0051082unfolded protein bindingIEAmolecular_function
GO:0051084'de novo' posttranslational protein foldingTASbiological_process
GO:0006457protein foldingTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0044267cellular protein metabolic processTASbiological_process
GO:0016272prefoldin complexIEAcellular_component
GO:0003714transcription corepressor activityTASmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005737cytoplasmTAScellular_component
GO:0045892negative regulation of transcription, DNA-dependenIMPbiological_process


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