| UniProt/SwissProt ID: | PFD5_HUMAN |
| Description: | prefoldin subunit 5 [Source:HGNC Symbol;Acc:8869] |
| Location: | chr12 q13.13 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y90 | DVGTGyYVEKT | Prefoldin | PhosphoSitePlus |
| Y91 | VGTGYyVEKTA | Prefoldin | PhosphoSitePlus |
| Y71 | LTSSMyVPGKL | Prefoldin | PhosphoSitePlus |
| Dephosphorylation site |
| PFD5_HUMAN do not have dephosphorylation site. |
| Mutation site |
| PFD5_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000334188 | Non-small cell lung carcinoma | Metastasis | cell line | Down | 17537172 | |
| Hyperphosphorylation site |
| PFD5_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| STK11_HUMAN | PFD5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| STK16_HUMAN | PFD5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| PFD5_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0090090 | negative regulation of canonical Wnt receptor sign | IMP | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | TAS | biological_process |
| GO:0060041 | retina development in camera-type eye | IEA | biological_process |
| GO:0051082 | unfolded protein binding | IEA | molecular_function |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
| GO:0006457 | protein folding | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0044267 | cellular protein metabolic process | TAS | biological_process |
| GO:0016272 | prefoldin complex | IEA | cellular_component |
| GO:0003714 | transcription corepressor activity | TAS | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0005737 | cytoplasm | TAS | cellular_component |
| GO:0045892 | negative regulation of transcription, DNA-dependen | IMP | biological_process |