Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PEBB_HUMAN
Description:core-binding factor, beta subunit [Source:HGNC Symbol;Acc:1539]
Location:chr16 q22.1
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y85TPSREyVDLERCBF_betaPhosphoSitePlus
S173RQQDPsPGSNLHPRD
S176DPSPGsNLGGGHPRD
T150EARRRtREFEDCBF_betaPhosphoSitePlus
Y96EAGKVyLKAPMCBF_betaPhosphoSitePlus

Dephosphorylation site
PEBB_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000415151R9GCOSMICBreast Cancer20668451
ENSP00000415151R83*COSMICBreast Cancer20668451
ENSP00000415151E152*BIOMARTBreast Cancer21930507, 21930502
ENSP00000290858E152*BIOMARTBreast Cancer21930507, 21930502
ENSP00000290858R83*COSMICBreast Cancer20668451
ENSP00000290858P100ASjoblom2006, COSMIC, HPIBreast Cancer16959974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000290858Gastric CancerMetastasiscell lineDown0.3117022644
ENSP00000290858Gastric CancerMetastasiscell lineDown0.3117022644

Hyperphosphorylation site
PEBB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PEBB_HUMANCSF2_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
PEBB_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001503ossificationIEAbiological_process
GO:0005575cellular_componentNDcellular_component
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0030098lymphocyte differentiationIEAbiological_process
GO:0003713transcription coactivator activityIEAmolecular_function
GO:0048469cell maturationIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function
GO:0030099myeloid cell differentiationIEAbiological_process
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0060216definitive hemopoiesisIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0001649osteoblast differentiationIEAbiological_process
GO:0005634nucleusIEAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23