| UniProt/SwissProt ID: | PDXL2_HUMAN |
| Description: | podocalyxin-like 2 [Source:HGNC Symbol;Acc:17936] |
| Location: | chr3 q21.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S492 | CQARAsQVRSD | CD34_antigen | PhosphoSitePlus |
| T209 | RDFSLtSSSQT | PhosphoSitePlus; HPRD | |
| S596 | RDPEDsDVFEE | CD34_antigen | PhosphoSitePlus |
| S570 | QEKHPsLNGGG | CD34_antigen | PhosphoSitePlus |
| S596 | RDPEDsDVFEE | HPRD; phosphoELM | |
| S570 | QEKHPsLNGGG | HPRD | |
| S212 | SLTSSsQTPGA | PhosphoSitePlus; HPRD | |
| S210 | DFSLTsSSQTP | PhosphoSitePlus; HPRD | |
| S220 | PGATKsRHEDS | PhosphoSitePlus; HPRD | |
| Dephosphorylation site |
| PDXL2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000345359 | G388E | COSMIC | Skin Cancer | 21984974 | ENSP00000345359 | G28S | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000345359 | G339R | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000345359 | E366K | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000345359 | R370K | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000345359 | G339R | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| PDXL2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PDXL2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PDXL2_HUMAN | LYAM1_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| PDXL2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0050901 | leukocyte tethering or rolling | IDA | biological_process |
| GO:0005539 | glycosaminoglycan binding | TAS | molecular_function |