Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PDIP3_HUMAN
Description:polymerase (DNA-directed), delta interacting protein 3 [Source:HGNC Symbol;Acc:23782]
Location:chr22 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S368LRLSDsPSMKKPhosphoSitePlus
S246AEPVLsPLEGTHPRD
T106RKQQTtVPQKPPeptidase_M49PhosphoSitePlus
S127SLKRSsPAAFIHPRD; phosphoELM; RegPhos
S383PRRVNsASSSNPhosphoSitePlus
S126ISLKRsSPAAFPeptidase_M49PhosphoSitePlus
Y236VQNDAyTAPALPhosphoSitePlus
T140PIGTVtPALKLHPRD; phosphoELM
T237QNDAYtAPALPPhosphoSitePlus
S405KALFKsSGASVPhosphoSitePlus
T329KDDAItAYKKYRRM_1PhosphoSitePlus
S5DELIHPRD
S339LRLSDsPSMKKHPRD
S275AEPVLsPLEGTPhosphoSitePlus; phosphoELM; RegPhos
S5_MADIsLDELIPhosphoSitePlus
S63QKIGLsDARLKPeptidase_M49PhosphoSitePlus
T106RKQQTtVPQKPHPRD
S126ISLKRsSPAAFHPRD; phosphoELM
S409KSSGAsVTTQPPhosphoSitePlus
S42QQGLLsQSTRTHPRD; phosphoELM; RegPhos
T105SRKQQtTVPQKHPRD
S42QQGLLsQSTRTPeptidase_M49PhosphoSitePlus
T105SRKQQtTVPQKPeptidase_M49PhosphoSitePlus
S63QKIGLsDARLKHPRD
S127SLKRSsPAAFIPeptidase_M49PhosphoSitePlus
S385RVNSAsSSNPPPhosphoSitePlus; phosphoELM; RegPhos
S406ALFKSsGASVTPhosphoSitePlus; phosphoELM; RegPhos
T140PIGTVtPALKLPeptidase_M49PhosphoSitePlus
S383PRRVNsASSSNp70S6KphosphoELM; RegPhos

Dephosphorylation site
PDIP3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000252115E186KCOSMICHead and Neck Cancer21798893

Differential expressed protein
PDIP3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PDIP3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANPDIP3_HUMANkinase -> substrateRegPhos
KS6B1_HUMANPDIP3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PDIP3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003723RNA bindingIEAmolecular_function
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0000166nucleotide bindingIEAmolecular_function
GO:0045727positive regulation of translationIMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005634nucleusIDAcellular_component
GO:0035145exon-exon junction complexIDAcellular_component
GO:0016607nuclear speckIDAcellular_component
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005737cytoplasmTAScellular_component


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