| UniProt/SwissProt ID: | PDIP3_HUMAN |
| Description: | polymerase (DNA-directed), delta interacting protein 3 [Source:HGNC Symbol;Acc:23782] |
| Location: | chr22 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S368 | LRLSDsPSMKK | PhosphoSitePlus | |
| S246 | AEPVLsPLEGT | HPRD | |
| T106 | RKQQTtVPQKP | Peptidase_M49 | PhosphoSitePlus |
| S127 | SLKRSsPAAFI | HPRD; phosphoELM; RegPhos | |
| S383 | PRRVNsASSSN | PhosphoSitePlus | |
| S126 | ISLKRsSPAAF | Peptidase_M49 | PhosphoSitePlus |
| Y236 | VQNDAyTAPAL | PhosphoSitePlus | |
| T140 | PIGTVtPALKL | HPRD; phosphoELM | |
| T237 | QNDAYtAPALP | PhosphoSitePlus | |
| S405 | KALFKsSGASV | PhosphoSitePlus | |
| T329 | KDDAItAYKKY | RRM_1 | PhosphoSitePlus |
| S5 | DELI | HPRD | |
| S339 | LRLSDsPSMKK | HPRD | |
| S275 | AEPVLsPLEGT | PhosphoSitePlus; phosphoELM; RegPhos | |
| S5 | _MADIsLDELI | PhosphoSitePlus | |
| S63 | QKIGLsDARLK | Peptidase_M49 | PhosphoSitePlus |
| T106 | RKQQTtVPQKP | HPRD | |
| S126 | ISLKRsSPAAF | HPRD; phosphoELM | |
| S409 | KSSGAsVTTQP | PhosphoSitePlus | |
| S42 | QQGLLsQSTRT | HPRD; phosphoELM; RegPhos | |
| T105 | SRKQQtTVPQK | HPRD | |
| S42 | QQGLLsQSTRT | Peptidase_M49 | PhosphoSitePlus |
| T105 | SRKQQtTVPQK | Peptidase_M49 | PhosphoSitePlus |
| S63 | QKIGLsDARLK | HPRD | |
| S127 | SLKRSsPAAFI | Peptidase_M49 | PhosphoSitePlus |
| S385 | RVNSAsSSNPP | PhosphoSitePlus; phosphoELM; RegPhos | |
| S406 | ALFKSsGASVT | PhosphoSitePlus; phosphoELM; RegPhos | |
| T140 | PIGTVtPALKL | Peptidase_M49 | PhosphoSitePlus |
| S383 | PRRVNsASSSN | p70S6K | phosphoELM; RegPhos |
| Dephosphorylation site |
| PDIP3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000252115 | E186K | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| PDIP3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PDIP3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | PDIP3_HUMAN | kinase -> substrate | RegPhos |
| KS6B1_HUMAN | PDIP3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| PDIP3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0000166 | nucleotide binding | IEA | molecular_function |
| GO:0045727 | positive regulation of translation | IMP | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0035145 | exon-exon junction complex | IDA | cellular_component |
| GO:0016607 | nuclear speck | IDA | cellular_component |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | TAS | cellular_component |