| UniProt/SwissProt ID: | PDGFD_HUMAN |
| Description: | platelet derived growth factor D [Source:HGNC Symbol;Acc:30620] |
| Location: | chr11 q22.3 |
| Node attribute: | ligand |
|
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|
| Y327 | KTVKKyHEVLQ | PDGF | PhosphoSitePlus |
| T273 | KRYSCtPRNYS | PDGF | PhosphoSitePlus |
|
PDGFD_HUMAN do not have dephosphorylation site.
|
|
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|
| ENSP00000302193 | D196Y | Sjoblom2006 | Intestines Cancer | 16959974, 21930507, 21930502 |
ENSP00000376865 | A267S | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000376865 | D202Y | HPI | Colorectal Cancer | 16959974 | ENSP00000302193 | D196Y | BIOMART | Colorectal Cancer | 21930507, 21930502 | ENSP00000376865 | D202Y | COSMIC | Intestines Cancer | 16959974 |
|
| PDGFD_HUMAN is not differential expressed protein. |
|
| PDGFD_HUMAN do not have hyperphosphorylation site. |
|
| GO ID | GO_Term | Evidence | Ontology |
|---|
| GO:0005788 | endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0071230 | cellular response to amino acid stimulus | IEA | biological_process |
| GO:0007275 | multicellular organismal development | IEA | biological_process |
| GO:0051781 | positive regulation of cell division | IEA | biological_process |
| GO:0008083 | growth factor activity | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | IEA | biological_process |
|
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Stack trace:
#0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli))
#1 {main}
thrown in
/usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line
23
