| UniProt/SwissProt ID: | PDCD2_HUMAN |
| Description: | programmed cell death 2 [Source:HGNC Symbol;Acc:8762] |
| Location: | chr6 q27 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y300 | PQLLNyLKADR | PDCD2_C | PhosphoSitePlus |
| Dephosphorylation site |
| PDCD2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000375940 | W279R | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| PDCD2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PDCD2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| BTK_HUMAN | PDCD2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK4_HUMAN | PDCD2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| PDCD2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0006915 | apoptotic process | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0012501 | programmed cell death | IEA | biological_process |