Phosphorylation

Protein information

UniProt/SwissProt ID:	PAR6A_HUMAN
Description:	par-6 partitioning defective 6 homolog alpha (C. elegans) [Source:HGNC Symbol;Acc:15943]
Location:	chr16 q22.1
Node attribute:	PPI(target)

Position	PhosphoPeptide	Source
S277	PAEPDsDDDSS	HPRD
S108	AFASNsLQRRK	HPRD
S345	DGSGFsL____	PhosphoSitePlus
S278	PAEPDsDDDSS	PhosphoSitePlus; HPRD; phosphoELM
S281	DSDDDsSDLVI	HPRD
S282	DSDDDsSDLVI	HPRD; phosphoELM

PAR6A_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000219255	E97ER	BIOMART	Pancreatic Cancer	21930507, 21930502
ENSP00000219255	*347S	COSMIC	Ovarian Cancer	21720365
ENSP00000219255	R262C	COSMIC	Ovarian Cancer	21720365
ENSP00000392388	R261C	TCGA	Ovarian Cancer	21720365, 18772890
ENSP00000219255	*347C	COSMIC	Ovarian Cancer	21720365

PAR6A_HUMAN is not differential expressed protein.

PAR6A_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
CDC42_HUMAN	PAR6A_HUMAN	other	KEGG

KEGG Pathway

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0005886	plasma membrane	TAS	cellular_component
GO:0007179	transforming growth factor beta receptor signaling	TAS	biological_process
GO:0016032	viral reproduction	TAS	biological_process
GO:0005515	protein binding	IEA	molecular_function
GO:0030742	GTP-dependent protein binding	ISS	molecular_function
GO:0051301	cell division	IEA	biological_process
GO:0005080	protein kinase C binding	IEA	molecular_function
GO:0001726	ruffle	IEA	cellular_component
GO:0030742	GTP-dependent protein binding	IEA	molecular_function
GO:0017048	Rho GTPase binding	ISS	molecular_function
GO:0005938	cell cortex	IEA	cellular_component
GO:0045217	cell-cell junction maintenance	IEA	biological_process
GO:0005829	cytosol	TAS	cellular_component
GO:0017048	Rho GTPase binding	IEA	molecular_function
GO:0005515	protein binding	IPI	molecular_function
GO:0034329	cell junction assembly	TAS	biological_process
GO:0045177	apical part of cell	IEA	cellular_component
GO:0070830	tight junction assembly	TAS	biological_process
GO:0045216	cell-cell junction organization	TAS	biological_process
GO:0005634	nucleus	IEA	cellular_component
GO:0045217	cell-cell junction maintenance	ISS	biological_process
GO:0005923	tight junction	ISS	cellular_component
GO:0005634	nucleus	ISS	cellular_component
GO:0005737	cytoplasm	IEA	cellular_component
GO:0007049	cell cycle	IEA	biological_process
GO:0008134	transcription factor binding	TAS	molecular_function
GO:0043234	protein complex	IEA	cellular_component
GO:0005923	tight junction	IEA	cellular_component

Human Phosphorylation Mediated
Signaling Transduction Network