Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PAR6A_HUMAN
Description:par-6 partitioning defective 6 homolog alpha (C. elegans) [Source:HGNC Symbol;Acc:15943]
Location:chr16 q22.1
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S277PAEPDsDDDSSHPRD
S108AFASNsLQRRKHPRD
S345DGSGFsL____PhosphoSitePlus
S278PAEPDsDDDSSPhosphoSitePlus; HPRD; phosphoELM
S281DSDDDsSDLVIHPRD
S282DSDDDsSDLVIHPRD; phosphoELM

Dephosphorylation site
PAR6A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000219255E97ERBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000219255*347SCOSMICOvarian Cancer21720365
ENSP00000219255R262CCOSMICOvarian Cancer21720365
ENSP00000392388R261CTCGAOvarian Cancer21720365, 18772890
ENSP00000219255*347CCOSMICOvarian Cancer21720365

Differential expressed protein
PAR6A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PAR6A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDC42_HUMANPAR6A_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04530Tight junction
hsa04144Endocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneTAScellular_component
GO:0007179transforming growth factor beta receptor signalingTASbiological_process
GO:0016032viral reproductionTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0030742GTP-dependent protein bindingISSmolecular_function
GO:0051301cell divisionIEAbiological_process
GO:0005080protein kinase C bindingIEAmolecular_function
GO:0001726ruffleIEAcellular_component
GO:0030742GTP-dependent protein bindingIEAmolecular_function
GO:0017048Rho GTPase bindingISSmolecular_function
GO:0005938cell cortexIEAcellular_component
GO:0045217cell-cell junction maintenanceIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0017048Rho GTPase bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0034329cell junction assemblyTASbiological_process
GO:0045177apical part of cellIEAcellular_component
GO:0070830tight junction assemblyTASbiological_process
GO:0045216cell-cell junction organizationTASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0045217cell-cell junction maintenanceISSbiological_process
GO:0005923tight junctionISScellular_component
GO:0005634nucleusISScellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0007049cell cycleIEAbiological_process
GO:0008134transcription factor bindingTASmolecular_function
GO:0043234protein complexIEAcellular_component
GO:0005923tight junctionIEAcellular_component


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