| UniProt/SwissProt ID: | NUDC_HUMAN |
| Description: | nuclear distribution C homolog (A. nidulans) [Source:HGNC Symbol;Acc:8045] |
| Location: | chr1 p36.11 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S136 | QLKNGsLDSPG | PhosphoSitePlus; HPRD | |
| S260 | SRLVSsDPEIN | PhosphoSitePlus | |
| S259 | WSRLVsSDPEI | PhosphoSitePlus | |
| T40 | FLRRKtDFFIG | PhosphoSitePlus | |
| T108 | QIKELtDEEAE | PhosphoSitePlus; HPRD; SysPTM | |
| T266 | DPEINtKKINP | PhosphoSitePlus | |
| Y292 | VEKMMyDQRQK | PhosphoSitePlus | |
| S285 | DSETRsMVEKM | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| Y223 | IDGELyNEVKV | CS | PhosphoSitePlus |
| T145 | PGKQDtEEDEE | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| S274 | INPENsKLSDL | PLK1 | HPRD; phosphoELM; RegPhos |
| S326 | PEMDFsKAK | PLK1 | HPRD; phosphoELM |
| S281 | LSDLDsETRSM | PhosphoSitePlus | |
| T58 | KLITQtFSHHN | PhosphoSitePlus | |
| S274 | INPENsKLSDL | PhosphoSitePlus | |
| S326 | PEMDFsKAKFN | PLK1 | RegPhos |
| S139 | NGSLDsPGKQD | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| S326 | PEMDFsKAKFN | PhosphoSitePlus | |
| S277 | ENSKLsDLDSE | PhosphoSitePlus | |
| Y223 | IDGELyNEVKV | HPRD | |
| Dephosphorylation site |
| NUDC_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000319664 | G141E | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000319664 | G141E | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| NUDC_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NUDC_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PLK1_HUMAN | NUDC_HUMAN | kinase -> substrate | RegPhos; Robert H Newman (2013) |
| ZAGL2_HUMAN | NUDC_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| NUDC_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0000910 | cytokinesis | TAS | biological_process |
| GO:0000087 | M phase of mitotic cell cycle | TAS | biological_process |
| GO:0008283 | cell proliferation | TAS | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0000278 | mitotic cell cycle | TAS | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0000236 | mitotic prometaphase | TAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007275 | multicellular organismal development | TAS | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005874 | microtubule | IEA | cellular_component |