| UniProt/SwissProt ID: | NTNG1_HUMAN |
| Description: | netrin G1 [Source:HGNC Symbol;Acc:23319] |
| Location: | chr1 p13.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T304 | CNLHAtVCVYD | PhosphoSitePlus | |
| Y308 | ATVCVyDNSKL | PhosphoSitePlus | |
| S311 | CVYDNsKLTCE | PhosphoSitePlus | |
| Dephosphorylation site |
| NTNG1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000359091 | D195N | COSMIC | Melanoma | 21499247 | ENSP00000359085 | E397Q | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000359091 | R5K | COSMIC | Melanoma | 21499247 | ENSP00000359091 | M87I | COSMIC | Ovarian Cancer | 21720365 | ENSP00000359091 | D66Y | COSMIC | Intestines Cancer | 17932254 | ENSP00000359091 | R336Q | COSMIC | Intestines Cancer | 17932254 | ENSP00000359091 | Y286* | COSMIC | Ovarian Cancer | 21720365 | ENSP00000294649 | A287P | BIOMART | Brain Cancer | 21930507, 21930502 |
| Differential expressed protein |
| NTNG1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NTNG1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NTNG1_HUMAN | LRC4C_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04360 | Axon guidance |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007409 | axonogenesis | IEA | biological_process |
| GO:0046658 | anchored to plasma membrane | IEA | cellular_component |
| GO:0046658 | anchored to plasma membrane | ISS | cellular_component |
| GO:0007409 | axonogenesis | ISS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | IEA | cellular_component |