Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NSF1C_HUMAN
Description:NSFL1 (p97) cofactor (p47) [Source:HGNC Symbol;Acc:15912]
Location:chr20 p13
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T354ADESQtLKEANSpt20; UBXPhosphoSitePlus
Y155FAGGGyRLGAAPhosphoSitePlus
S241VLSTSsPAQQAHPRD
Y167EEESAyVAGEKPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S192WKSGFsLDNGESpt20; SEPPhosphoSitePlus
S176EKRQHsSQDVHHPRD; RegPhos
S114PPRKKsPNELVPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S177KRQHSsQDVHVHPRD
S176EKRQHsSQDVHSpt20PhosphoSitePlus
S272VLSTSsPAQQASpt20PhosphoSitePlus
T73SDNRVtSFRDLPhosphoSitePlus
S177KRQHSsQDVHVSpt20PhosphoSitePlus
S140ERVTKsPGETSCDC2(CDK1RegPhos; SysPTM
S271QVLSTsSPAQQHPRD; phosphoELM
Y95EGQRFyAGGSEPhosphoSitePlus
S140ERVTKsPGETSCDK1HPRD; phosphoELM; SysPTM
S29RFFLEsAGWDLCDC2RegPhos
S165APEEEsAYVAGPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S240QVLSTsSPAQQHPRD
S272VLSTSsPAQQAHPRD; phosphoELM; RegPhos
S74DNRVTsFRDLIHPRD; phosphoELM; RegPhos
S140ERVTKsPGETSPhosphoSitePlus; phosphoELM; SysPTM
S140ERVTKsPGETSCDC2RegPhos; SysPTM

Dephosphorylation site
NSF1C_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000371074R88KBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000338643R168KBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000216879R199KBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000418529R201KBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000371074Hepatocellular CarcinomaNormal vs. CancertissueUp2.915759316

Hyperphosphorylation site
NSF1C_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANNSF1C_HUMANkinase -> substrateRegPhos
CDK1_HUMANNSF1C_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04141Protein processing in endoplasmic reticulum

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005694chromosomeIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0008289lipid bindingIEAmolecular_function
GO:0005795Golgi stackIEAcellular_component
GO:0005634nucleusIEAcellular_component


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