Phosphorylation

Protein information

UniProt/SwissProt ID:	NR1D1_HUMAN
Description:	nuclear receptor subfamily 1, group D, member 1 [Source:HGNC Symbol;Acc:7962]
Location:	chr17 q21.1
Node attribute:	TF; gene

Position	PhosphoPeptide	Source
S85	SPSSSsSSSSS	PhosphoSitePlus
S55	TYFPPsPTGSL	PhosphoSitePlus
S59	PSPTGsLTQDP	PhosphoSitePlus
S84	GSPSSsSSSSS	PhosphoSitePlus
Y394	CPTHVyAAPEG	PhosphoSitePlus
S23	GSSGSsPSRTS	PhosphoSitePlus; HPRD; phosphoELM
S86	PSSSSsSSSSS	PhosphoSitePlus
S87	SSSSSsSSSSS	PhosphoSitePlus

NR1D1_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000246672	E219K	COSMIC	Head and Neck Cancer	21798893
ENSP00000246672	V479M	COSMIC	Melanoma
ENSP00000246672	N313S	COSMIC	Head and Neck Cancer	21798893

NR1D1_HUMAN is not differential expressed protein.

NR1D1_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
NR1D1_HUMAN	BMAL1_HUMAN	TF -> target gene	KEGG
RORA_HUMAN	NR1D1_HUMAN	TF -> target gene	TRANSFAC
NR1D1_HUMAN	NR1D1_HUMAN	TF -> target gene	TRANSFAC

KEGG Pathway

KEGG ID	Pathway
hsa04710	Circadian rhythm - mammal

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0044212	transcription regulatory region DNA binding	IDA	molecular_function
GO:0004879	ligand-activated sequence-specific DNA binding RNA	TAS	molecular_function
GO:0000790	nuclear chromatin	IDA	cellular_component
GO:0008270	zinc ion binding	IEA	molecular_function
GO:0010871	negative regulation of receptor biosynthetic proce	IMP	biological_process
GO:0003677	DNA binding	IEA	molecular_function
GO:0007623	circadian rhythm	IEA	biological_process
GO:0005634	nucleus	IEA	cellular_component
GO:0000122	negative regulation of transcription from RNA poly	IMP	biological_process
GO:0006367	transcription initiation from RNA polymerase II pr	TAS	biological_process
GO:0003714	transcription corepressor activity	TAS	molecular_function
GO:0010467	gene expression	TAS	biological_process
GO:0003700	sequence-specific DNA binding transcription factor	IEA	molecular_function
GO:0005634	nucleus	TAS	cellular_component
GO:0006355	regulation of transcription, DNA-dependent	IEA	biological_process
GO:0003707	steroid hormone receptor activity	IEA	molecular_function
GO:0071222	cellular response to lipopolysaccharide	IMP	biological_process
GO:0043565	sequence-specific DNA binding	IEA	molecular_function
GO:0005654	nucleoplasm	TAS	cellular_component
GO:0030522	intracellular receptor mediated signaling pathway	TAS	biological_process
GO:0034144	negative regulation of toll-like receptor 4 signal	IMP	biological_process
GO:0043401	steroid hormone mediated signaling pathway	IEA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network