Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NR1D1_HUMAN
Description:nuclear receptor subfamily 1, group D, member 1 [Source:HGNC Symbol;Acc:7962]
Location:chr17 q21.1
Node attribute:TF; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S85SPSSSsSSSSSPhosphoSitePlus
S55TYFPPsPTGSLPhosphoSitePlus
S59PSPTGsLTQDPPhosphoSitePlus
S84GSPSSsSSSSSPhosphoSitePlus
Y394CPTHVyAAPEGPhosphoSitePlus
S23GSSGSsPSRTSPhosphoSitePlus; HPRD; phosphoELM
S86PSSSSsSSSSSPhosphoSitePlus
S87SSSSSsSSSSSPhosphoSitePlus

Dephosphorylation site
NR1D1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000246672E219KCOSMICHead and Neck Cancer21798893
ENSP00000246672V479MCOSMICMelanoma
ENSP00000246672N313SCOSMICHead and Neck Cancer21798893

Differential expressed protein
NR1D1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NR1D1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NR1D1_HUMANBMAL1_HUMANTF -> target geneKEGG
RORA_HUMANNR1D1_HUMANTF -> target geneTRANSFAC
NR1D1_HUMANNR1D1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04710Circadian rhythm - mammal

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0044212transcription regulatory region DNA bindingIDAmolecular_function
GO:0004879ligand-activated sequence-specific DNA binding RNATASmolecular_function
GO:0000790nuclear chromatinIDAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0010871negative regulation of receptor biosynthetic proceIMPbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0007623circadian rhythmIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0000122negative regulation of transcription from RNA polyIMPbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0003714transcription corepressor activityTASmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005634nucleusTAScellular_component
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0003707steroid hormone receptor activityIEAmolecular_function
GO:0071222cellular response to lipopolysaccharideIMPbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0030522intracellular receptor mediated signaling pathwayTASbiological_process
GO:0034144negative regulation of toll-like receptor 4 signalIMPbiological_process
GO:0043401steroid hormone mediated signaling pathwayIEAbiological_process


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