Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NPFF2_HUMAN
Description:neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:4525]
Location:chr4 q13.3
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S280TIMSPsAVMLH7tm_1; TMPhosphoSitePlus
Y465KPMEAyALKAKPhosphoSitePlus

Dephosphorylation site
NPFF2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000307822C455RCOSMICOvarian Cancer21720365
ENSP00000307822A459SCOSMICHead and Neck Cancer21798893
ENSP00000351599Y204CBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000307822W115CCOSMICHead and Neck Cancer21798893
ENSP00000307822V353ACOSMICCentral Nervous System Neoplasms18772396
ENSP00000307822I149VCOSMICOvarian Cancer21720365
ENSP00000340789*133KCOSMICMelanoma21499247

Differential expressed protein
NPFF2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NPFF2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NPFF_HUMANNPFF2_HUMANligand -> receptorHPMR
IP3KA_HUMANNPFF2_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0015629actin cytoskeletonIDAcellular_component
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0008188neuropeptide receptor activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0009582detection of abiotic stimulusTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process


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