Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NPBW2_HUMAN
Description:neuropeptides B/W receptor 2 [Source:HGNC Symbol;Acc:4530]
Location:chr20 q13.33
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y143MSVDRyLVVLA7tm_1PhosphoSitePlus
Y126LAVDHyNIFSS7tm_1; TMPhosphoSitePlus
Y133IFSSIyFLAVM7tm_1; TMPhosphoSitePlus

Dephosphorylation site
NPBW2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358783G92RSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000358783G92RHPIColorectal Cancer16959974
ENSP00000358783R161WCOSMICHead and Neck Cancer21798893

Differential expressed protein
NPBW2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NPBW2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NPW_HUMANNPBW2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0038003opioid receptor signaling pathwayTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0016021integral to membraneICcellular_component
GO:0007186G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0004985opioid receptor activityTASmolecular_function


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