| UniProt/SwissProt ID: | NPBW1_HUMAN |
| Description: | neuropeptides B/W receptor 1 [Source:HGNC Symbol;Acc:4522] |
| Location: | chr8 q11.23 |
| Node attribute: | receptor; PPI(target) |
| Phosphorylation site |
| NPBW1_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| NPBW1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000330284 | T323I | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000330284 | T323I | COSMIC | Ovarian Cancer | 21720365 | ENSP00000330284 | P19Q | Sjoblom2006, COSMIC, HPI | Breast Cancer | 16959974 |
| Differential expressed protein |
| NPBW1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NPBW1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NPW_HUMAN | NPBW1_HUMAN | ligand -> receptor | HPMR |
| NPB_HUMAN | NPBW1_HUMAN | ligand -> receptor | HPMR |
| IP3KA_HUMAN | NPBW1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0004985 | opioid receptor activity | TAS | molecular_function |
| GO:0019222 | regulation of metabolic process | IEA | biological_process |
| GO:0007268 | synaptic transmission | TAS | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | IDA | biological_process |
| GO:0016021 | integral to membrane | IC | cellular_component |
| GO:0038003 | opioid receptor signaling pathway | TAS | biological_process |