Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NONO_HUMAN
Description:non-POU domain containing, octamer-binding [Source:HGNC Symbol;Acc:7871]
Location:chrX q13.1
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T418PPGPAtMMPDGPhosphoSitePlus
Y267SFEYEyAMRWKNOPSPhosphoSitePlus
S188DRGRPsGKGIVRRM_1PhosphoSitePlus
T410PVPAGtPAPPGPhosphoSitePlus
S209ALDRCsEGSFLHPRD
T431GLTPPtTERFGPhosphoSitePlus
T151HSASLtVRNLPRRM_1PhosphoSitePlus
T432LTPPTtERFGQPhosphoSitePlus; HPRD; SysPTM
S149ACHSAsLTVRNRRM_1PhosphoSitePlus; SysPTM
Y265PGSFEyEYAMRNOPSPhosphoSitePlus
S149ACHSAsLTVRNHPRD; SysPTM
T424MMPDGtLGLTPPhosphoSitePlus; HPRD
T428GTLGLtPPTTEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S262FAQPGsFEYEYNOPSPhosphoSitePlus
T450GAIGGtPPAFNPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y471NKRRRy_____PhosphoSitePlus
S147RFACHsASLTVPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S188DRGRPsGKGIVHPRD
T15EKQNHtPRKHHPhosphoSitePlus; HPRD
T440FGQAAtMEGIGPhosphoSitePlus; HPRD; SysPTM

Dephosphorylation site
NONO_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000362963F213LCOSMICOvarian Cancer21720365
ENSP00000362947F213LTCGAOvarian Cancer21720365, 18772890
ENSP00000276079F213LTCGAOvarian Cancer21720365, 18772890
ENSP00000362963F213LTCGAOvarian Cancer21720365, 18772890
ENSP00000276079F213LCOSMICOvarian Cancer21720365
ENSP00000362947F213LCOSMICOvarian Cancer21720365
ENSP00000276079R256SCOSMICHead and Neck Cancer21798893
ENSP00000362963R256SCOSMICHead and Neck Cancer21798893
ENSP00000362947R256SCOSMICHead and Neck Cancer21798893

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000362947Testicular CancerNormal vs. Cancercell lineUp18489135
ENSP00000362947Gastric CancerTreatment (none vs. drug-resistant)cell lineDown0.6520625496

Hyperphosphorylation site
NONO_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NONO_HUMANMPCP_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
NONO_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003723RNA bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0042802identical protein bindingIPImolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0006310DNA recombinationIEAbiological_process
GO:0005730nucleolusIEAcellular_component
GO:0000166nucleotide bindingIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0016607nuclear speckIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0006397mRNA processingIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusTAScellular_component
GO:0006281DNA repairIEAbiological_process
GO:0042382paraspecklesIDAcellular_component
GO:0016363nuclear matrixIDAcellular_component
GO:0008380RNA splicingIEAbiological_process


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