| UniProt/SwissProt ID: | NMUR1_HUMAN |
| Description: | neuromedin U receptor 1 [Source:HGNC Symbol;Acc:4518] |
| Location: | chr2 q37.1 |
| Node attribute: | receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S171 | PLQARsMVTRA | 7tm_1 | PhosphoSitePlus |
| Y160 | LSVERyVAVVH | 7tm_1; TM | PhosphoSitePlus |
| T174 | ARSMVtRAHVR | 7tm_1 | PhosphoSitePlus |
| Dephosphorylation site |
| NMUR1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000305877 | L11F | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000305877 | W186C | COSMIC | Pancreatic Cancer |
| Differential expressed protein |
| NMUR1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| NMUR1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NMU_HUMAN | NMUR1_HUMAN | ligand -> receptor | HPMR |
| NMS_HUMAN | NMUR1_HUMAN | ligand -> receptor | HPMR |
| IP3KA_HUMAN | NMUR1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0019722 | calcium-mediated signaling | IDA | biological_process |
| GO:0008188 | neuropeptide receptor activity | TAS | molecular_function |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0007200 | phospholipase C-activating G-protein coupled recep | IDA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0048016 | inositol phosphate-mediated signaling | IDA | biological_process |
| GO:0008188 | neuropeptide receptor activity | IEA | molecular_function |
| GO:0007218 | neuropeptide signaling pathway | TAS | biological_process |
| GO:0007202 | activation of phospholipase C activity | IDA | biological_process |
| GO:0007218 | neuropeptide signaling pathway | IEA | biological_process |
| GO:0006821 | chloride transport | IDA | biological_process |
| GO:0006816 | calcium ion transport | IDA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0016021 | integral to membrane | IDA | cellular_component |
| GO:0006939 | smooth muscle contraction | IEP | biological_process |
| GO:0001607 | neuromedin U receptor activity | IDA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |