Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NKG2D_HUMAN
Description:killer cell lectin-like receptor subfamily K, member 1 [Source:HGNC Symbol;Acc:18788]
Location:chr12 p13.2
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S16HSWEMsEFHNYPhosphoSitePlus
Y209STPNTyICMQRLectin_CPhosphoSitePlus
S12RRSRHsWEMSEPhosphoSitePlus
S9IRGRRsRHSWEPhosphoSitePlus
T205IENCStPNTYILectin_CPhosphoSitePlus

Dephosphorylation site
NKG2D_HUMAN do not have dephosphorylation site.

Mutation site
NKG2D_HUMAN do not have mutation site.

Differential expressed protein
NKG2D_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NKG2D_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
N2DL2_HUMANNKG2D_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04650Natural killer cell mediated cytotoxicity
hsa05144Malaria
hsa04650Natural killer cell mediated cytotoxicity
hsa05144Malaria

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007165signal transductionTASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0009986cell surfaceIEAcellular_component
GO:0030101natural killer cell activationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0016021integral to membraneTAScellular_component
GO:0045954positive regulation of natural killer cell mediateIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0045429positive regulation of nitric oxide biosynthetic pIEAbiological_process
GO:0050830defense response to Gram-positive bacteriumIEAbiological_process
GO:0030246carbohydrate bindingIEAmolecular_function
GO:0032394MHC class Ib receptor activityIEAmolecular_function
GO:0071222cellular response to lipopolysaccharideIEAbiological_process
GO:0050776regulation of immune responseTASbiological_process
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0042288MHC class I protein bindingIEAmolecular_function
GO:0004872receptor activityTASmolecular_function
GO:0031295T cell costimulationTASbiological_process
GO:0009897external side of plasma membraneIEAcellular_component
GO:0002223stimulatory C-type lectin receptor signaling pathwIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0032729positive regulation of interferon-gamma productionIEAbiological_process